6d0a: Difference between revisions

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-'''Unreleased structure'''
-The entry 6d0a is ON HOLD
+==Crystal structure of Kynurenine Aminotransferase-II in apo-form, at 1.47 A resolution==
+<StructureSection load='6d0a' size='340' side='right' caption='[[6d0a]], [[Resolution|resolution]] 1.47&Aring;' scene=''>
-Authors: Jayawickrama, G.S., Sun, G., Nematollahi, A., Church, W.B.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6d0a]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6D0A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6D0A FirstGlance]. <br>
-Description: Crystal structure of Kynurenine Aminotransferase-II in apo-form, at 1.47 A resolution
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6d0a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6d0a OCA], [http://pdbe.org/6d0a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6d0a RCSB], [http://www.ebi.ac.uk/pdbsum/6d0a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6d0a ProSAT]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
-[[Category: Church, W.B]]
+== Function ==
+[[http://www.uniprot.org/uniprot/AADAT_HUMAN AADAT_HUMAN]] Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro).<ref>PMID:18620547</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Church, W B]]
+[[Category: Jayawickrama, G S]]
 [[Category: Nematollahi, A]]
-[[Category: Jayawickrama, G.S]]
 [[Category: Sun, G]]
+[[Category: Alpha-beta fold]]
+[[Category: Hexahistidine tag]]
+[[Category: Plp-dependent]]
+[[Category: Transferase]]