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==Structure of full-length H11A mutant form of TIGAR from Danio rerio== | ==Structure of full-length H11A mutant form of TIGAR from Danio rerio== | ||
<StructureSection load='3e9e' size='340' side='right' caption='[[3e9e]], [[Resolution|resolution]] 2.10Å' scene=''> | <StructureSection load='3e9e' size='340' side='right' caption='[[3e9e]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3dcy|3dcy]], [[3e9c|3e9c]], [[3e9d|3e9d]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3dcy|3dcy]], [[3e9c|3e9c]], [[3e9d|3e9d]]</td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">zgc:56074 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7955 Brachidanio rerio])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">zgc:56074 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7955 Brachidanio rerio])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3e9e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e9e OCA], [http://pdbe.org/3e9e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3e9e RCSB], [http://www.ebi.ac.uk/pdbsum/3e9e PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3e9e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e9e OCA], [http://pdbe.org/3e9e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3e9e RCSB], [http://www.ebi.ac.uk/pdbsum/3e9e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3e9e ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
Revision as of 12:06, 25 October 2017
Structure of full-length H11A mutant form of TIGAR from Danio rerioStructure of full-length H11A mutant form of TIGAR from Danio rerio
Structural highlights
Function[TIGRB_DANRE] Fructose-bisphosphatase hydrolyzing fructose-2,6-bisphosphate as well as fructose-1,6-bisphosphate. Inhibits glycolysis by reducing cellular levels of fructose-2,6-bisphosphate. May protect cells against reactive oxygen species and against apoptosis induced by tp53. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. |
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