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Structure of full-length H11A mutant form of TIGAR from Danio rerioStructure of full-length H11A mutant form of TIGAR from Danio rerio
Structural highlights
FunctionTIGRB_DANRE Fructose-bisphosphatase hydrolyzing fructose-2,6-bisphosphate as well as fructose-1,6-bisphosphate. Inhibits glycolysis by reducing cellular levels of fructose-2,6-bisphosphate. May protect cells against reactive oxygen species and against apoptosis induced by tp53. Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. |
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