3e9c: Difference between revisions

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==Structure of a tryptic core fragment of TIGAR from Danio rerio==
==Structure of a tryptic core fragment of TIGAR from Danio rerio==
<StructureSection load='3e9c' size='340' side='right' caption='[[3e9c]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='3e9c' size='340' side='right' caption='[[3e9c]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3dcy|3dcy]], [[3e9d|3e9d]], [[3e9e|3e9e]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3dcy|3dcy]], [[3e9d|3e9d]], [[3e9e|3e9e]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">zgc:56074 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7955 Brachidanio rerio])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">zgc:56074 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7955 Brachidanio rerio])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3e9c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e9c OCA], [http://pdbe.org/3e9c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3e9c RCSB], [http://www.ebi.ac.uk/pdbsum/3e9c PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3e9c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e9c OCA], [http://pdbe.org/3e9c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3e9c RCSB], [http://www.ebi.ac.uk/pdbsum/3e9c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3e9c ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==

Revision as of 12:06, 25 October 2017

Structure of a tryptic core fragment of TIGAR from Danio rerioStructure of a tryptic core fragment of TIGAR from Danio rerio

Structural highlights

3e9c is a 2 chain structure with sequence from Brachidanio rerio. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Gene:zgc:56074 (Brachidanio rerio)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[TIGRB_DANRE] Fructose-bisphosphatase hydrolyzing fructose-2,6-bisphosphate as well as fructose-1,6-bisphosphate. Inhibits glycolysis by reducing cellular levels of fructose-2,6-bisphosphate. May protect cells against reactive oxygen species and against apoptosis induced by tp53.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

3e9c, resolution 2.00Å

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