5svc: Difference between revisions
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==Mechanism of ATP-Dependent Acetone Carboxylation, Acetone Carboxylase nucleotide-free structure== | |||
<StructureSection load='5svc' size='340' side='right' caption='[[5svc]], [[Resolution|resolution]] 2.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5svc]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5SVC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5SVC FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
[[Category: | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5svb|5svb]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetone_carboxylase Acetone carboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.4.1.6 6.4.1.6] </span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5svc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5svc OCA], [http://pdbe.org/5svc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5svc RCSB], [http://www.ebi.ac.uk/pdbsum/5svc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5svc ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/ACXB_XANP2 ACXB_XANP2]] Catalyzes the carboxylation of acetone to form acetoacetate. Has a reduced activity on butanone, and no activity on 2-pentatone, 3-pentatone, 2-hexanone, chloroacetone, pyruvate, phosphoenolpyruvate, acetaldehyde, propionaldehyde and propylene oxide.<ref>PMID:9237998</ref> [[http://www.uniprot.org/uniprot/ACXC_XANP2 ACXC_XANP2]] Catalyzes the carboxylation of acetone to form acetoacetate. Has a reduced activity on butanone, and no activity on 2-pentatone, 3-pentatone, 2-hexanone, chloroacetone, pyruvate, phosphoenolpyruvate, acetaldehyde, propionaldehyde and propylene oxide.<ref>PMID:9237998</ref> [[http://www.uniprot.org/uniprot/ACXA_XANP2 ACXA_XANP2]] Catalyzes the carboxylation of acetone to form acetoacetate. Has a reduced activity on butanone, and no activity on 2-pentatone, 3-pentatone, 2-hexanone, chloroacetone, pyruvate, phosphoenolpyruvate, acetaldehyde, propionaldehyde and propylene oxide.<ref>PMID:9237998</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Acetone carboxylase]] | |||
[[Category: Alleman, A B]] | |||
[[Category: Dubois, J L]] | |||
[[Category: Eilers, B J]] | |||
[[Category: Kabasakal, B V]] | |||
[[Category: Murray, J W]] | |||
[[Category: Mus, F]] | |||
[[Category: Nocek, B P]] | |||
[[Category: Peters, J W]] | |||
[[Category: Acetoacetate]] | |||
[[Category: Ligase]] |