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==Crystal Structure of Isoform 2 of Purine Nucleoside Phosphorylase from Schistosoma mansoni in complex with cytosine and ribose-1-phosphate== | |||
<StructureSection load='5ko6' size='340' side='right' caption='[[5ko6]], [[Resolution|resolution]] 1.42Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5ko6]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KO6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KO6 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CYT:6-AMINOPYRIMIDIN-2(1H)-ONE'>CYT</scene>, <scene name='pdbligand=R1P:RIBOSE-1-PHOSPHATE'>R1P</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5cxq|5cxq]], [[5cqs|5cqs]], [[5ko5|5ko5]]</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Purine-nucleoside_phosphorylase Purine-nucleoside phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.1 2.4.2.1] </span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ko6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ko6 OCA], [http://pdbe.org/5ko6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ko6 RCSB], [http://www.ebi.ac.uk/pdbsum/5ko6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ko6 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/A0A0U3AGT1_SCHMA A0A0U3AGT1_SCHMA]] The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.[PIRNR:PIRNR000477] | |||
==See Also== | |||
*[[Purine nucleoside phosphorylase|Purine nucleoside phosphorylase]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Purine-nucleoside phosphorylase]] | ||
[[Category: Bird, L]] | |||
[[Category: Brandao-Neto, J]] | [[Category: Brandao-Neto, J]] | ||
[[Category: | [[Category: Owens, R]] | ||
[[Category: | [[Category: Pereira, H M]] | ||
[[Category: Romanello, L]] | [[Category: Romanello, L]] | ||
[[Category: | [[Category: Torini, J R]] | ||
[[Category: Transferase]] | |||
Revision as of 10:32, 6 October 2017
Crystal Structure of Isoform 2 of Purine Nucleoside Phosphorylase from Schistosoma mansoni in complex with cytosine and ribose-1-phosphateCrystal Structure of Isoform 2 of Purine Nucleoside Phosphorylase from Schistosoma mansoni in complex with cytosine and ribose-1-phosphate
Structural highlights
Function[A0A0U3AGT1_SCHMA] The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.[PIRNR:PIRNR000477] See Also |
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