RNA ligase: Difference between revisions

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<StructureSection load='1vgj' size='350' side='right' scene='RNA_ligase/Cv/1' caption='Se-Met RNA ligase (PDB code [[1vgj]])'>
<StructureSection load='1vgj' size='350' side='right' scene='RNA_ligase/Cv/1' caption='Se-Met RNA ligase (PDB code [[1vgj]])'>
'''RNA ligase''' (LigR) is an enzyme which ligates two ribonucleotide chains using ATP and producing AMP, diphosphate and the ligated ribonucleotide chain<ref>PMID:18972386</ref>.  See more details in [[T4 RNA ligase 2 (Rnl2)]] and [[Ligases]].
'''RNA ligase''' (LigR) is an enzyme which ligates two ribonucleotide chains using ATP and producing AMP, diphosphate and the ligated ribonucleotide chain<ref>PMID:18972386</ref>.  See more details in [[T4 RNA ligase 2 (Rnl2)]] and [[Ligases]].
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|
*RNA ligase
**[[2c5u]] – T4LigR 1 RNA-binding domain - Enterobacteria phage T4<br />
**[[1s68]] - T4LigR 2 N-terminal<br />
**[[1vgj]], [[1vdx]] – PyLigR – ''Pyrococcus horikoshii''<br />
**[[2vug]] – LigR – ''Pyrococcus abyssi''<br />
**[[5cot]] – NgLigR – ''Naegleria gruberi''<br />
**[[1xdn]] – LigR 1 editing – ''Trypanosoma brucei''<br />
**[[1iuh]] – LigR 2’-5’ – ''Thermus thermophilus''<br />
**[[5cot]] – aLigR – amoeba<br />


[[2hvr]], [[2hvs]] – T4LigR 2 + DNA + nucleotide – Enterobacteria phage T4<br />
* RNA ligase complex
[[1s68]] - T4LigR 2 N-terminal<br />
[[2c5u]] – T4LigR 1 RNA-binding domain<br />
[[1vgj]], [[1vdx]] – LigR – ''Pyrococcus horikoshii''<br />
[[2vug]] – LigR – ''Pyrococcus abyssi''<br />
[[1xdn]] – LigR 1 editing – ''Trypanosoma brucei''<br />
[[1iuh]] – LigR 2’-5’ – ''Thermus thermophilus''<br />
[[4qak]] - LigR 2’-5’ – ''Escherichia coli''<br />
[[5cot]] – aLigR – amoeba<br />
[[5cou]] – aLigR + ATP<br />
[[5d1o]], [[5d1p]] – LigR ATP-dependent + ATP – ''Methanothermobacter thermautotrophicus''<br />


**[[5tt6]] – T4LigR 1 + ATP<br />
**[[2hvr]], [[2hvs]] – T4LigR 2 + DNA + nucleotide <br />
**[[2hvq]] - T4LigR 2 + adenosine derivative<br />
**[[4qak]] - LigR 2’-5’ + AMP – ''Escherichia coli''<br />
**[[5cou]] – aLigR + ATP<br />
**[[5d1o]], [[5d1p]] – LigR ATP-dependent + ATP – ''Methanothermobacter thermautotrophicus''<br />
**[[4isz]] – PhLigR RtcB + GTP + Mn<br />
**[[4dwq]], [[4it0]] – PhLigR RtcB + GMP + Mn<br />
**[[4isj]], [[4dwr]] – PhLigR RtcB + Mn<br />
**[[5cou]] – NgLigR (mutant) + ATP + Mn<br />
**[[5cov]] – NgLigR + Mn<br />
}}
== References ==
== References ==
<references/>
<references/>


[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 20:59, 2 October 2017

RNA ligase (LigR) is an enzyme which ligates two ribonucleotide chains using ATP and producing AMP, diphosphate and the ligated ribonucleotide chain[1]. See more details in T4 RNA ligase 2 (Rnl2) and Ligases.


Se-Met RNA ligase (PDB code 1vgj)

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3D Structures of RNA ligase3D Structures of RNA ligase

Updated on 02-October-2017

ReferencesReferences

  1. Nichols NM, Tabor S, McReynolds LA. RNA ligases. Curr Protoc Mol Biol. 2008 Oct;Chapter 3:Unit3.15. doi:, 10.1002/0471142727.mb0315s84. PMID:18972386 doi:http://dx.doi.org/10.1002/0471142727.mb0315s84

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Michal Harel, Alexander Berchansky, Joel L. Sussman