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==Crystal Structure of Enoyl-Acyl Carrier Protein Reductase (FabI) from Neisseria meningitidis in complex with NAD+ and Triclosan==
==Crystal Structure of Enoyl-Acyl Carrier Protein Reductase (FabI) from Neisseria meningitidis in complex with NAD+ and Triclosan==
<StructureSection load='4m89' size='340' side='right' caption='[[4m89]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='4m89' size='340' side='right' caption='[[4m89]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4m89]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Neisseria_meningitidis_fam18 Neisseria meningitidis fam18]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M89 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4M89 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4m89]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Neimf Neimf]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M89 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4M89 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=TCL:TRICLOSAN'>TCL</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=TCL:TRICLOSAN'>TCL</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4m86|4m86]], [[4m87|4m87]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4m86|4m86]], [[4m87|4m87]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fabI, NMC1834 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272831 Neisseria meningitidis FAM18])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fabI, NMC1834 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272831 NEIMF])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m89 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m89 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4m89 RCSB], [http://www.ebi.ac.uk/pdbsum/4m89 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m89 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m89 OCA], [http://pdbe.org/4m89 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4m89 RCSB], [http://www.ebi.ac.uk/pdbsum/4m89 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4m89 ProSAT]</span></td></tr>
</table>
</table>


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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Neisseria meningitidis fam18]]
[[Category: Neimf]]
[[Category: Forwood, J K]]
[[Category: Forwood, J K]]
[[Category: Nanson, J D]]
[[Category: Nanson, J D]]

Revision as of 11:38, 11 August 2016

Crystal Structure of Enoyl-Acyl Carrier Protein Reductase (FabI) from Neisseria meningitidis in complex with NAD+ and TriclosanCrystal Structure of Enoyl-Acyl Carrier Protein Reductase (FabI) from Neisseria meningitidis in complex with NAD+ and Triclosan

Structural highlights

4m89 is a 2 chain structure with sequence from Neimf. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Gene:fabI, NMC1834 (NEIMF)
Activity:[acyl-carrier-protein_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number 1.3.1.9
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

See Also

4m89, resolution 1.90Å

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