Mandelate racemase

Function Mandelate rasemase (MAR) catalyzes the interconversion of enantiomers of mandelate (S to R). MAR is Mg-dependent. MAR can racemize other alpha-hydroxy carbonyl compounds. MAR is involved in aromatic acids catabolism. Structural highlights The active site of MAR binds the reaction intermediate.

spinqualitylabelsall models Structure of mandelate racemase complex with reaction intermediate phenyl-lactate and Mg+2 ion (green) (PDB entry 1mdr) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

3D structures of mandelate racemase3D structures of mandelate racemase

Updated on 17-April-2016

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• mandelate racemase
  • 2mnr – PpMAR – Pseudomonas putida
    
  • 2hzg – MAR – Rhodobacter sphaeroides
    
  • 2og9, 3bjs – MAR – Polaromonas
    
  • 2pmq, 2rdx, 3u4f, 3fvd, 2qdd – MAR – Roseovarius
    
  • 2qde – MAR – Azoarcus
    
  • 3ik4 – MAR – Herpetosiphon aurantiacus
    
  • 3mqt, 3sjn – MAR – Shewanella pealeana
    
  • 3n4e, 4dwd – MAR – Paracoccus denitrificans
    
  • 3n4f – GeMAR – Geobacillus
    
  • 3msy, 3no1 – MAR – Marine actinobacterium
    
  • 3n6h, 3n6j – MAR – Actinobacillus succinogenes
    
  • 3ddm - BbMAR (mutant) – Bordetella bronchiseptica
    
  • 3h12 – BbMAR
    
  • 3ssz – MAR – Rhodobacteraceae bacterium
    
  • 3t4w – MAR – Sulfitobacter
    
  • 3t8q – MAR – Hoeflea phototrophica
    
  • 3u9i – MAR – Roseiflexus
    
  • 4dx3, 4e8g, 3tj4, 3tji – AtMAR – Agrobacterium tumefaciens
    
  • 3s47 – MAR – Clostridium beijerincki
    
  • 4dhg, 3vc5, 3vc6 – MAR – Thermobispora bispora
    
  • 4e4f – MAR – Pectobacterium carotovorum
    
  • 3thu – MAR – Sphingomonas
    
  • 3toy – BrMAR – Bradyrhizobium
    
  • 3ugv – MAR – alpha proteobacterium
    
  • 2pod – MAR – Burkholderia pseudomallei
    
  • 3dfh - VbMAR – Vibrionales bacterium
    
• Mandelate racemase binary complex
  • 1mns, 1mdr – PpMAR + α-phenyl lactate
    
  • 3ops – GeMAR + lactate
    
  • 1mra, 1dtn – PpMAR (mutant) + atrolactate
    
  • 1mdl - PpMAR (mutant) + mandelate
    
  • 4hnc - PpMAR (mutant) + benzilic acid
    
  • 4m6u - PpMAR + tartronic acid
    
  • 4fp1 – PpMAR + inhibitor
    
  • 3tte - BrMAR + mandelate
    
  • 3uxk, 3uxl – PpMAR + intermediate analog
    
  • 3sbf – VbMAR (mutant) + arabinonate
    
  • 3r25 – VbMAR + glycerol
    
  • 4gfi – AtMAR + dipeptide epimerase
    
  • 4h19 – AtMAR + ribonohydroxamate