Ire1: Difference between revisions

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== Structural highlights ==
== Structural highlights ==


Yeast Ire1 structure contains 3 phosphorylated residues: <scene name='51/516469/Cv/2'>2 Ser and a Thr</scene>.  Ire1 shows a different binding site for ADP and for quercetin.  Quercetin is a powerful activator of Ire1.  Ire1 binds 2 molecules of quercetin at its dimer interface<ref>PMID:23880584</ref>.  
Yeast Ire1 structure contains 3 phosphorylated residues: <scene name='51/516469/Cv/2'>2 Ser and a Thr</scene>.  Ire1 shows a different <scene name='51/516469/Cv/6'>binding site for ADP</scene> and for quercetin.  Quercetin is a powerful activator of Ire1.  Ire1 binds 2 molecules of quercetin at its dimer interface<ref>PMID:23880584</ref>.  


==3D structures of Ire1==
==3D structures of Ire1==

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Michal Harel, Alexander Berchansky