NADPH dehydrogenase

Function NADPH dehydrogenase or old yellow enzyme (OYE) catalyzes the conversion of NADPH, H+ and acceptor to NADP+ and reduced acceptor. See NAD(P)H. The acceptor is a quinone. OYE is a flavoenzyme with two cofactors: FAD and FMN.

spinqualitylabelsall models Structure of yeast NADPH dehydrogenase complex with FMN and p-hydroxybenzaldehyde (PDB code 1oyb). Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

3D Structures of NADPH dehydrogenase3D Structures of NADPH dehydrogenase

Updated on 16-February-2016

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• NADPH dehydrogenase
  • 1oyc, 1oya, 4rnu, 4rnw, 4rnx – yOYE + FMN - yeast
    
  • 1k02, 4h6k, 4k7y – yOYE (mutant) + FMN
    
  • 1bwk, 1bwl – OYE (mutant) + FMN - Candida albicans
    
  • 3gr7, 3gr8 – OYE + FMN – Geobacillus kaustophilus
    
  • 4qai – SsOYE + FMN – Scheffersomyces stipitis
    
• NADPH dehydrogenase complexes
  • 1oyb, 4rnv – yOYE + FMN + p-hydroxybenzaldehyde
    
  • 1k03 – yOYE (mutant) + FMN + p-hydroxybenzaldehyde
    
  • 3rnd – yOYE (mutant) + FMN + hydroxymethyl cyclopent-2-en-one
    
  • 4gbu, 4gxm – yOYE (mutant) + FMN + methyl propenyl phenol
    
  • 4ge8, 3txz, 4gwe, 4h4i, 4k7v, 4k8e, 4k8h – yOYE (mutant) + FMN + carvone
    
  • 3tx9 – yOYE + FMN + hydroxymethyl cyclopent-2-en-one
    
  • 3tjl, 4m5p – SsOYE + FMN + malonate
    
  • 3upw – SsOYE + FMN + malonate + nicotineamide
    
  • 4df2 – SsOYE + FMN + malonate + chlorophenol