Ecotin: Difference between revisions

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{{STRUCTURE_1id5|  PDB=1id5 | SIZE=400| SCENE= |right|CAPTION=A monomer of the dimeric E. coli ecotin (gold) complex with thrombin heavy chain (pink) and light chain (aqua), protease inhibitor and Ca+2 ion (green) [[1id5]] }}
<StructureSection load='1id5' size='400' side='right' scene='' caption='A monomer of the dimeric E. coli ecotin (gold) complex with thrombin heavy chain (pink) and light chain (aqua), protease inhibitor and Ca+2 ion (green) [[1id5]]'>


'''Ecotin''' (ECO) is a serine protease inhibitor found in the periplasm of ''E. coli''.  It is a potent anti and a reversible tight-binding inhibitor of human factor Xa.<ref>PMID:14705961</ref>
'''Ecotin''' (ECO) is a serine protease inhibitor found in the periplasm of ''E. coli''.  It is a potent anti and a reversible tight-binding inhibitor of human factor Xa.<ref>PMID:14705961</ref>
 
</StructureSection>
== 3D Structures of Ecotin ==
== 3D Structures of Ecotin ==



Revision as of 15:24, 8 February 2016


Ecotin (ECO) is a serine protease inhibitor found in the periplasm of E. coli. It is a potent anti and a reversible tight-binding inhibitor of human factor Xa.[1]

A monomer of the dimeric E. coli ecotin (gold) complex with thrombin heavy chain (pink) and light chain (aqua), protease inhibitor and Ca+2 ion (green) 1id5

Drag the structure with the mouse to rotate

3D Structures of Ecotin3D Structures of Ecotin

Updated on 08-February-2016

ReferencesReferences

  1. Eggers CT, Murray IA, Delmar VA, Day AG, Craik CS. The periplasmic serine protease inhibitor ecotin protects bacteria against neutrophil elastase. Biochem J. 2004 Apr 1;379(Pt 1):107-18. PMID:14705961 doi:http://dx.doi.org/10.1042/BJ20031790

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky