Fatty acid-binding protein: Difference between revisions
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<StructureSection load='1fe3' size='350' side='right' scene='48/487562/Cv/ | <StructureSection load='1fe3' size='350' side='right' scene='48/487562/Cv/3' caption='Human brain-type fatty acid-binding protein complex with oleate (PDB code [[1fe3]]) '> | ||
'''Fatty acid-binding protein''' (FABP) are carrier proteins for fatty acids and other lipophilic substances. They facilitate the transfer of fatty acids between extra- and intracellular membranes. FABS coordinate lipid trafficking and signaling in cells<ref>PMID:16424607</ref>. Various FABS differ in their tissue expression. '''IFABP''' is intestinal; '''HFABP''' is heart-type; '''BFABP''' is brain-type; '''LFABP''' is liver-type; '''AFABP''' is adipocyte; '''LMDABP''' is from flight muscle; '''TFABP''' is from testis; '''EXFABP''' is extracellular. | '''Fatty acid-binding protein''' (FABP) are carrier proteins for fatty acids and other lipophilic substances. They facilitate the transfer of fatty acids between extra- and intracellular membranes. FABS coordinate lipid trafficking and signaling in cells<ref>PMID:16424607</ref>. Various FABS differ in their tissue expression. '''IFABP''' is intestinal; '''HFABP''' is heart-type; '''BFABP''' is brain-type; '''LFABP''' is liver-type; '''AFABP''' is adipocyte; '''LMDABP''' is from flight muscle; '''TFABP''' is from testis; '''EXFABP''' is extracellular. | ||
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== Structural insights == | == Structural insights == | ||
The <scene name='48/487562/Cv/2'>FABP active site binds fatty acids</scene><ref>PMID:10854433</ref>. | The <scene name='48/487562/Cv/2'>FABP active site binds fatty acids</scene> ({{Template:ColorKey_Hydrophobic}}, {{Template:ColorKey_Polar}})<ref>PMID:10854433</ref>. | ||
</StructureSection> | </StructureSection> | ||