Cell death protein: Difference between revisions

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<StructureSection load='3bik' size='400' side='right' scene= caption='Human CED-1 extracellular domain.  Programmed cell death protein 1 (green and pink) and programmed cell death 1 ligand 1 (grey) complex with CED-1 ligand 1 and glycerol (PDB code [[3bik]])'>
<StructureSection load='3bik' size='400' side='right' scene= caption='Human CED-1 extracellular domain.  Programmed cell death protein 1 (green and pink) and programmed cell death 1 ligand 1 (grey) complex with CED-1 ligand 1 and glycerol (PDB code [[3bik]])'>
</StructureSection>


'''Cell death proteins''' or '''Programmed cell death protein''' or '''CD279''' (CED) are involved in the process of cellular apoptosis.  '''CED-1''' is a T cell regulator.  CED-1 is expressed on the surface of T cells, B cells and macrophages.  It is a membrane protein and acts in suppressing the immune system during pregnancy, tissue allografts, autoimmune diseases and hepatitis.  CED-1 has 2 ligands: CED-L1 and CED-L2.  Formation of CED-1/CED-L1 complex reduces T cell proliferation at the lymph nodes.  For details on '''CED-4''' see [[CED-4 Apoptosome]].
'''Cell death proteins''' or '''Programmed cell death protein''' or '''CD279''' (CED) are involved in the process of cellular apoptosis.  '''CED-1''' is a T cell regulator.  CED-1 is expressed on the surface of T cells, B cells and macrophages.  It is a membrane protein and acts in suppressing the immune system during pregnancy, tissue allografts, autoimmune diseases and hepatitis.  CED-1 has 2 ligands: CED-L1 and CED-L2.  Formation of CED-1/CED-L1 complex reduces T cell proliferation at the lymph nodes.  For details on '''CED-4''' see [[CED-4 Apoptosome]].
 
</StructureSection>
==3D structures of cell death protein==
==3D structures of cell death protein==


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Michal Harel, Alexander Berchansky