Cell death protein: Difference between revisions
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{{STRUCTURE_3bik| PDB=3bik | SIZE=400| SCENE= |right|CAPTION= Human CED-1 extracellular domain. Programmed cell death protein 1 (green and pink) and programmed cell death 1 ligand 1 (grey) complex with CED-1 ligand 1 and glycerol [[3bik]] }} | {{STRUCTURE_3bik| PDB=3bik | SIZE=400| SCENE= |right|CAPTION= Human CED-1 extracellular domain. Programmed cell death protein 1 (green and pink) and programmed cell death 1 ligand 1 (grey) complex with CED-1 ligand 1 and glycerol [[3bik]] }} | ||
</StructureSection> | |||
'''Cell death proteins''' or '''Programmed cell death protein''' or '''CD279''' (CED) are involved in the process of cellular apoptosis. CED-1 is a T cell regulator. CED-1 is expressed on the surface of T cells, B cells and macrophages. It is a membrane protein and acts in suppressing the immune system during pregnancy, tissue allografts, autoimmune diseases and hepatitis. CED-1 has 2 ligands: CED-L1 and CED-L2. Formation of CED-1/CED-L1 complex reduces T cell proliferation at the lymph nodes. For details on CED-4 see [[CED-4 Apoptosome]]. | '''Cell death proteins''' or '''Programmed cell death protein''' or '''CD279''' (CED) are involved in the process of cellular apoptosis. CED-1 is a T cell regulator. CED-1 is expressed on the surface of T cells, B cells and macrophages. It is a membrane protein and acts in suppressing the immune system during pregnancy, tissue allografts, autoimmune diseases and hepatitis. CED-1 has 2 ligands: CED-L1 and CED-L2. Formation of CED-1/CED-L1 complex reduces T cell proliferation at the lymph nodes. For details on CED-4 see [[CED-4 Apoptosome]]. | ||