2a1y: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2a1y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A1Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2A1Y FirstGlance]. <br> | <table><tr><td colspan='2'>[[2a1y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A1Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2A1Y FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ypf|1ypf]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ypf|1ypf]]</td></tr> | ||
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">guaC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1392 Bacillus anthracis])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">guaC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1392 Bacillus anthracis])</td></tr> | ||
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/GMP_reductase GMP reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.7.1.7 1.7.1.7] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/GMP_reductase GMP reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.7.1.7 1.7.1.7] </span></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2a1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a1y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2a1y RCSB], [http://www.ebi.ac.uk/pdbsum/2a1y PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2a1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a1y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2a1y RCSB], [http://www.ebi.ac.uk/pdbsum/2a1y PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/GUAC_BACAN GUAC_BACAN]] Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity). | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Bacillus anthracis]] | [[Category: Bacillus anthracis]] | ||
[[Category: GMP reductase]] | [[Category: GMP reductase]] | ||
[[Category: Blagova, E V | [[Category: Blagova, E V]] | ||
[[Category: Brannigan, J A | [[Category: Brannigan, J A]] | ||
[[Category: Fogg, M J | [[Category: Fogg, M J]] | ||
[[Category: Grenha, R | [[Category: Grenha, R]] | ||
[[Category: Levdikov, V M | [[Category: Levdikov, V M]] | ||
[[Category: SPINE, Structural Proteomics in Europe | [[Category: SPINE, Structural Proteomics in Europe]] | ||
[[Category: Wilkinson, A J | [[Category: Wilkinson, A J]] | ||
[[Category: Wilson, K S | [[Category: Wilson, K S]] | ||
[[Category: And nucleotides: nucleotide and nucleoside interconversion]] | [[Category: And nucleotides: nucleotide and nucleoside interconversion]] | ||
[[Category: Gmp]] | [[Category: Gmp]] | ||
Revision as of 03:37, 25 December 2014
Crystal Structure of GuaC-GMP complex from Bacillus anthracis at 2.26 A Resolution.Crystal Structure of GuaC-GMP complex from Bacillus anthracis at 2.26 A Resolution.
Structural highlights
Function[GUAC_BACAN] Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity). Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. |
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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Bacillus anthracis
- GMP reductase
- Blagova, E V
- Brannigan, J A
- Fogg, M J
- Grenha, R
- Levdikov, V M
- SPINE, Structural Proteomics in Europe
- Wilkinson, A J
- Wilson, K S
- And nucleotides: nucleotide and nucleoside interconversion
- Gmp
- Guac
- Nucleoside
- Oxidoreductase
- Purine
- Pyrimidine
- Spine
- Structural genomic
- Structural proteomics in europe