Thrombin: Difference between revisions

===Thrombin===

[[3pmb]] - bThr HC + LC – bovine<br />

[[3qgn]] - hThr HC (mutant) + LC – human<br />

[[3r3g]] - hThr HC + LC <br />

[[2hnt]]– hThr-γ HC + LC<br />

[[3jz1]], [[3jz2]], [[2od3]] - hThr HC + LC (mutant) <br />

[[3gic]] - hThr HC + LC<br />

[[3ee0]], [[2a0q]], [[1sg8]], [[1sgi]], [[1jou]] - hThr HC (mutant) + LC<br />

[[3edx]], [[3hk3]], [[3hk6]] - mThr HC (mutant) + LC – mouse<br />

[[2ocv]] - mThr HC + LC

''Thrombin complexes''

[[3pma]] – bThr HC + LC residues 336-364 + sucrose octasulfate<br />  

[[1dlk]] - bThr HC + LC + peptide inhibitor<br />

[[3hki]] - mThr HC (mutant) + LC + proteinase-activated receptor 1 peptide<br />

[[3hkj]] - hThr HC (mutant) + LC + proteinase-activated receptor 1 peptide<br />

[[2pux]] - mThr HC + LC + proteinase-activated receptor 3 peptide<br />

[[2pv9]] - mThr HC (mutant) + LC + proteinase-activated receptor 4 peptide<br />

[[1dm4]] - mThr HC (mutant) + LC + fibrinogen peptide<br />

[[1ycp]], [[1bbr]] – bThr-ε HC + LC + fibrinogen peptide<br />

[[1ucy]] - bThr HC + LC + fibrinogen peptide<br />

[[1fph]] - hThr HC + LC + fibrinogen peptide<br />

[[3bv9]] - hThr HC (mutant) + LC + peptide inhibitor<br />

[[2a2x]], [[1eb1]], [[1h8i]], [[1h8d]], [[1dit]], [[1hbt]], [[3u8t]] - hThr HC + LC + peptide inhibitor<br />

[[1g37]], [[1eoj]], [[1eol]], [[1nrn]], [[1nro]], [[1nrp]], [[1nrq]], [[1nrr]], [[1nrs]] - hThr HC + peptide inhibitor<br />

[[1hlt]] - hThr HC + LC + thrombomodulin peptide<br />

[[4ch2]], [[4ch8]] - hThr HC + LC + platelet glycoprotein IB α chain peptide <br />

[[2ank]], [[3po1]] - hThr HC + LC + peptide + inhibitor<br />

[[1bhx]], [[1abj]], [[1ppb]] - hThr HC + LC + inhibitor<br />

[[1uvs]], [[1uvt]], [[1uvu]] - bThr HC + LC + inhibitor<br />

[[1etr]], [[1ets]], [[1ett]] – bThr-ε HC + LC + inhibitor<br />

[[3dd2]] - hThr HC + LC + RNA<br />

[[1hao]], [[1hap]], [[1hut]] - hThr HC + LC + DNA<br />

[[3bf6]] - hThr HC + LC + suramin<br />

[[1xmn]] - hThr HC + LC + heparin<br />

[[2h9t]] - hThr HC + LC + suramin + PPACK<BR />

[[1z8i]], [[1z8j]] - hThr HC + LC (mutant) + PPACK<BR />

[[1sfq]], [[1shh]], [[2thf]], [[1thp]], [[1b7x]] - hThr HC (mutant) + LC + PPACK<BR />

[[1ook]] - hThr HC + LC + PPACK<BR />

[[2hpp]], [[2hpq]] - hThr HC + LC + PThr residues 214-292 + PPACK<BR />

''Thrombin complexes containing hirudin''

[[3c27]], [[2zc9]], [[2zda]], [[2zdv]], [[3egk]], [[2r2m]], [[2v3h]], [[2v3o]], [[2pks]], [[3eq0]], [[3dt0]], [[3dux]], [[3da9]], [[3dhk]], [[2znk]], [[2zo3]], [[3d49]], [[2zhe]], [[2zhf]], [[2zhw]], [[2zg0]], [[2zfq]], [[2zfr]], [[2zhq]], [[2zi2]], [[2ziq]], [[2zff]], [[2zfp]], [[2zgb]], [[2zgx]], [[2zf0]], [[3biu]], [[3biv]], [[2uuj]], [[2uuk]], [[2jh0]], [[2jh5]], [[2jh6]], [[2gde]], [[2bxt]], [[2bxu]], [[2bvr]], [[2bvs]], [[2bvx]], [[2bdy]], [[2feq]], [[2c8w]], [[2c8x]], [[2c8y]], [[2c8z]], [[2c90]], [[2c93]], [[2cf8]], [[2cf9]], [[2anm]], [[2w7g]], [[2fes]], [[1ype]], [[1ypg]], [[1ypj]], [[1ypk]], [[1ypl]], [[1ypm]], [[1vzq]], [[1way]], [[1wbg]], [[1riw]], [[1mu6]], [[1mu8]], [[1mue]], [[1nzq]], [[1o0d]], [[1oyt]], [[1o2g]], [[1gj4]], [[1gj5]], [[1kts]], [[1ktt]], [[1ghv]], [[1ghw]], [[1ghx]], [[1ghy]], [[1c5n]], [[1c5o]], [[1c4y]], [[1d3d]], [[1d3p]], [[1d3q]], [[1d3t]], [[1c4u]], [[1c4v]], [[1c1u]], [[1c1v]], [[1c1w]], [[1qj1]], [[1qj6]], [[1qj7]], [[1qhr]], [[1qur]], [[1d4p]], [[1ba8]], [[1bb0]], [[1ca8]], [[1awf]], [[1awh]], [[1bcu]], [[1a61]], [[1a3b]], [[1a3e]], [[1a46]], [[1a5g]], [[1b5g]], [[1tbz]], [[1a4w]], [[1ay6]], [[1ae8]], [[1afe]], [[1ad8]], [[1ai8]], [[1aix]], [[1bmm]], [[1bmn]], [[1lhc]], [[1lhd]], [[1lhe]], [[1lhf]], [[1lhg]], [[1uma]], [[1aht]], [[1fpc]], [[1w7g]], [[3ldx]], [[3p17]], [[3qto]], [[3qtv]], [[3qwc]], [[3qx5]], [[3rlw]], [[3rly]], [[3rm0]], [[3rm2]], [[3rml]], [[3rmm]], [[3rmn]], [[3rmo]], [[3t5f]], [[3sv2]], [[3si3]], [[3si4]], [[3sha]], [[3shc]], [[3u98]], [[3u9a]], [[3uwj]], [[4e7r]], [[4n3l]], [[4nze]] - hThr HC + LC + hirudin peptide + inhibitor<br />

[[1zgi]], [[1zgv]], [[1zrb]], [[1z71]], [[1xm1]], [[1sl3]], [[1ta2]], [[1ta6]], [[1nm6]], [[1nt1]], [[1doj]], [[1d9i]], [[1d6w]], [[1qbv]], [[1tmu]], [[1dwb]], [[1dwc]], [[1dwd]], [[1dwe]], [[4baq]], [[4bao]], [[4ban]], [[4bak]], [[4bam]], [[4bah]]- hThr HC + hirudin peptide + inhibitor<br />

[[1ny2]], [[8kme]], [[7kme]], [[1a2c]], [[1tom]], [[1hdt]], [[1tmt]], [[1tmb]], [[3u8o]], [[3u8r]] - hThr HC + LC + hirudin peptide + peptide inhibitor<br />

[[3hat]] - hThr HC + LC + hirudin peptide + fibrinogen peptide<br />

[[2uuf]], [[2pw8]], [[1no9]], [[1c5l]], [[1vr1]], [[4thn]], [[5gds]], [[1hxf]], [[1hxe]], [[1abi]], [[1hgt]], [[1ihs]], [[1iht]], [[1thr]], [[1ths]], [[2hgt]], [[3utu]], [[4ayv]], [[4ayy]], [[4az2]] - hThr HC + LC + hirudin peptide<br />

[[3vxe]], [[3vxf]] - hThr HC + LC + bivalirudin peptide<br />

[[4mlf]] - hThr HC (mutant) + LC + hirudin peptide<br />

[[1vit]] - bThr HC + LC + hirudin peptide<br />

''Thrombin complex with protein''

[[2a45]] - hThr HC + LC + fibrinogen α, β, γ chains<br />

[[2a1d]], [[1nu7]] – bThr HC + LC + staphylocoagulase<br />

[[1tb6]] - hThr HC + LC (mutant) + antithrombin<br />

[[2b5t]] - hThr HC (mutant) + LC + antithrombin III (mutant)<br />

[[4dt7]] - hThr HC (mutant) + LC + vitamin K-dependent protein C peptide<br />

[[1jmo]] - hThr HC (mutant) + LC + heparin cofactor II<br />  

[[4dy7]] - hThr HC (mutant) + LC + glia-derived nexin<br />

[[1e0f]] - hThr HC + LC + haemadin<br />

[[4boh]] - hThr HC + LC + madanin<br />

[[4e05]], [[4e06]] - hThr HC + LC + anophelin<br />

[[1dx5]] - hThr HC + LC + thrombomodulin<br />

[[3p6z]], [[3p70]] - hThr HC + LC + coagulation factor V<br />

[[1de7]] - hThr HC + LC + factor XIII activation peptide<br />

[[3pmh]] - hThr HC + LC + platelet glycoprotein IB α chain<br />

[[3b23]] - hThr HC + LC + variegin<br />

[[1avg]] - bThr HC + LC + triabin<br />

[[1bth]] - bThr HC (mutant) + LC (mutant) + BPTI<br />

[[1toc]] - bThr HC + LC + ornithodorin<br />

[[1tbq]], [[1tbr]] - bThr HC + LC + rhodniin<br />

[[1hrt]] - bThr HC + LC + hirudin<br />

[[3htc]], [[4htc]] - hThr HC + LC + hirudin

===Prothrombin===

[[3e6p]], [[2afq]], [[3u69]] - hPThr HC + LC<br />

[[3s7h]], [[3s7k]]– hPThr HC + LC (mutant) <br />

[[3bei]], [[2pgb]], [[2gp9]], [[1tq0]], [[1rd3]], [[4hzh]], [[4h6t]], [[4h6s]] - hPThr HC (mutant) + LC<br />

[[1mh0]] - hPThr HC (mutant) <br />

[[1nl1]], [[1nl2]], [[2spt]], [[2pf1]], [[2pf2]] – bPThr residues 1-156

''Prothrombin complexes''

[[3qdz]] – hPThr HC (mutant) + LC + proteinase-activated receptor 4 peptide<br />

[[3lu9]], [[3bef]] - hPThr HC + LC (mutant) + proteinase-activated receptor 1 peptide<br />

[[1sr5]] - hPThr HC + LC + antithrombin III<br />

[[3k65]] - hPThr HC residues 315-622 (mutant) + LC residues 199-314<br />

[[3f68]] - hPThr HC residues 364-622 + LC residues 328-363 + hirudin peptide<br />

[[1jwt]], [[3c1k]] - hPThr HC + inhibitor<br />

[[4hfy]], [[4hfp]] - hPThr HC (mutant) + LC + inhibitor<br />

[[2pgq]], [[1tq7]] - hPThr HC (mutant) + LC + PPACK<BR />

[[2cn0]], [[1t4u]], [[1t4v]], [[1sb1]], [[1k21]], [[1k22]], [[1g30]], [[1g32]], [[1o5g]], [[3tu7]] - hPThr HC + LC + hirudin peptide + inhibitor<br />

[[4ax9]] - hPThr HC + LC + hirudin peptide<br />

[[1twx]] - hPThr HC (mutant) + LC + hirudin peptide<br />

[[2hwl]] - hPThr HC (mutant) + LC + fibrinogen γ’ peptide<br />  

[[4i7y]] - hPThr HC + LC + DNA<br />

''Prothrombin complex with protein''

[[1id5]] - hPThr HC + LC + ecotin<br />

[[1p8v]] - hPThr HC + LC + platelet glycoprotein IB α chain<br />

[[3gis]] - hPThr HC residues 364-622 (mutant) + LC residues 315-363 + thrombomodulin<br />

[[3b9f]] - hPThr HC (mutant) + LC + protein C inhibitor<br />

[[2ody]] - hPThr HC + LC + boophilin

===Prethrombin-1===

[[3nxp]] - hThr residues 199-622

===Prethrombin-2===

[[1nu9]] – hThr + staphylocoagulase<br />

[[1mkw]], [[1mkx]] – hThr + bThr HC + LC<br />

[[1hag]], [[1hah]] – hThr + hirudin peptide<br />

[[1hai]] – hThr + inhibitor<br />

[[3sqe]], [[3sqh]] - hThr (mutant)

===Meizothrombin===