Succinate-semialdehyde dehydrogenase: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
</StructureSection>


==3D structures of succinate-semialdehyde dehydrogenase==
==3D structures of succinate-semialdehyde dehydrogenase==


Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|


===Succinate-semialdehyde dehydrogenase===
*Succinate-semialdehyde dehydrogenase


[[4it9]], [[3vz1]] – SySSD - ''Synechococcus''<br />
**[[4it9]], [[3vz1]] – SySSD - ''Synechococcus''<br />
[[3vz2]] – SySSD (mutant) <br />
**[[3vz2]] – SySSD (mutant) <br />
[[3ifg]], [[3ifh]] – SSD – ''Burkholderia pseudomallei''<br />
**[[3ifg]], [[3ifh]] – SSD – ''Burkholderia pseudomallei''<br />
[[3rh9]] – SSD – ''Marinobacter aquaeolei''<br />
**[[3rh9]] – SSD – ''Marinobacter aquaeolei''<br />
[[2w8n]], [[2w8o]] – hSSD - human <br />
**[[2w8n]], [[2w8o]] – hSSD - human <br />
[[2w8p]] – hSSD (mutant) <br />
**[[2w8p]] – hSSD (mutant) <br />


===Succinate-semialdehyde dehydrogenase complexes===
*Succinate-semialdehyde dehydrogenase complexes
 
[[2w8q]] – hSSD (mutant) + succinate<br />
[[2w8r]] – hSSD (mutant) + ADP<br />
[[4ita]] – SySSD + NADPH<br />
[[4itb]] – SySSD + NADPH + succinic semialdehyde<br />
[[3vz3]] – SySSD (mutant) + NADPH + succinic semialdehyde<br />
[[3jz4]] – SSD + NADPH – ''Escherichia coli''<br />


**[[2w8q]] – hSSD (mutant) + succinate<br />
**[[2w8r]] – hSSD (mutant) + ADP<br />
**[[4ita]] – SySSD + NADPH<br />
**[[4itb]] – SySSD + NADPH + succinic semialdehyde<br />
**[[3vz3]] – SySSD (mutant) + NADPH + succinic semialdehyde<br />
**[[3jz4]] – SSD + NADPH – ''Escherichia coli''<br />
}}


== References ==
== References ==

Revision as of 14:31, 10 December 2014


Function

Succinate-semialdehyde dehydrogenase (SSD) catalyzes the conversion of succinate semialdehyde, NAD+ and water to succinate, NADH and H+. SSD participates in glutamate and butyrate metabolism.

Disease

SSD deficiency.

Relevance

Structural highlights

Structure of succinate-semialdehyde dehydrogenase complex with NADPH and succinate semialdehyde (PDB code 3vz3).

Drag the structure with the mouse to rotate

3D structures of succinate-semialdehyde dehydrogenase3D structures of succinate-semialdehyde dehydrogenase

Updated on 10-December-2014

ReferencesReferences

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman
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