3jz4

Crystal structure of E. coli NADP dependent enzymeCrystal structure of E. coli NADP dependent enzyme

Structural highlights

3jz4 is a 4 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2.3Å
Ligands:
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

GABD_ECOLI Catalyzes the NADP(+)-dependent oxidation of succinate semialdehyde to succinate. It appears to be important for nitrogen metabolism under N limitation conditions.^[1] ^[2]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

↑ Langendorf CG, Key TL, Fenalti G, Kan WT, Buckle AM, Caradoc-Davies T, Tuck KL, Law RH, Whisstock JC. The X-ray crystal structure of Escherichia coli succinic semialdehyde dehydrogenase; structural insights into NADP+/enzyme interactions. PLoS One. 2010 Feb 18;5(2):e9280. PMID:20174634 doi:10.1371/journal.pone.0009280
↑ Donnelly MI, Cooper RA. Succinic semialdehyde dehydrogenases of Escherichia coli: their role in the degradation of p-hydroxyphenylacetate and gamma-aminobutyrate. Eur J Biochem. 1981 Jan;113(3):555-61. PMID:7011797

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OCA

[1] Langendorf CG, Key TL, Fenalti G, Kan WT, Buckle AM, Caradoc-Davies T, Tuck KL, Law RH, Whisstock JC. The X-ray crystal structure of Escherichia coli succinic semialdehyde dehydrogenase; structural insights into NADP+/enzyme interactions. PLoS One. 2010 Feb 18;5(2):e9280. PMID:20174634 doi:10.1371/journal.pone.0009280

[2] Donnelly MI, Cooper RA. Succinic semialdehyde dehydrogenases of Escherichia coli: their role in the degradation of p-hydroxyphenylacetate and gamma-aminobutyrate. Eur J Biochem. 1981 Jan;113(3):555-61. PMID:7011797

[1]

[2]

3jz4

Crystal structure of E. coli NADP dependent enzymeCrystal structure of E. coli NADP dependent enzyme

Structural highlights

Function

Evolutionary Conservation

See Also

References

Contents

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3jz4

Crystal structure of E. coli NADP dependent enzymeCrystal structure of E. coli NADP dependent enzyme

Structural highlights

Function

Evolutionary Conservation

See Also

References

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