Serpin: Difference between revisions

Revision as of 13:03, 10 December 2014

Serpin or serine protease inhibitor (Ser) are protease inhibitors.

Ser E1 is antithrombin.
Ser C1 is antithrombin.
Ser A5 is protein C inhibitor.
Ser A6 is a cortisol-binding globulin.
Ser A8 is angiotensinogen.
Ser A7 is a thyroxine-binding globulin.
Ser B1 is leukocyte elastase inhibitor.
Ser B3 is squamos cell carcinoma antigen 1.
Ser B5 is Maspin.
Ser I1 is neuroserpin.
Ser A10 is protein Z-related protease inhibitor.
Ser A1 is alpha-1 antitrypsin.
Ser A3 is α 1-antichymotrypsin.
Ser E1 is plasminogen activator inhibitor 1.

Structure of cleaved human serpin A1. Residues 46-382 (grey), residues 383-418 (green). (PDB entry 3ndd)

Drag the structure with the mouse to rotate

3D structures of serpin3D structures of serpin

Updated on 10-December-2014

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

@@ Line 16: / Line 16: @@
 * Ser A3 is α 1-antichymotrypsin.<br />
 * Ser E1 is plasminogen activator inhibitor 1.
+</StructureSection>
 ==3D structures of serpin==
 Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
+{{#tree:id=OrganizedByTopic|openlevels=0|
-===Ser===
+*Serpin
-[[1mtp]], [[1sng]] – Ser – ''Thermobifida fusca''
-===Ser A1===
-[[Alpha-1-antitrypsin]]
-===Ser A3 (α 1-antichymotrypsin)===
-[[2ach]], [[1as4]], [[3caa]] – hSer-A3<br />
-[[4caa]], [[1qmn]], [[3dlw]] – hSer-A3 (mutant)<br />
-[[1yxa]] – Ser-A3N - mouse<br />
-===Ser A5===
-[[2ol2]] – hSer-A5<br />
+**[[1mtp]], [[1sng]] – Ser – ''Thermobifida fusca''
-[[3dy0]] – hSer-A5 + heparin
-===Ser A6===
+*Serpin A1see [[Alpha-1-antitrypsin]]
-[[Corticosteroid-binding globulin]]
+*Serpin A3 (α 1-antichymotrypsin)
-===Ser A7===
+**[[2ach]], [[1as4]], [[3caa]] – hSer-A3<br />
+**[[4caa]], [[1qmn]], [[3dlw]] – hSer-A3 (mutant)<br />
+**[[1yxa]] – Ser-A3N - mouse<br />
-[[2riv]] – hSer-A7<br />
+*Serpin A5
-[[2riw]] – hSer-A7 + thyroxine<br />
-[[2xn3]] – hSer-A7 + mefenamic acid<br />
-[[2xn5]] – hSer-A7 + furosemide<br />
-[[2xn6]], [[2xn7]] – hSer-A7 + thyroxine-fluoresein
-===Ser A8===
+**[[2ol2]] – hSer-A5<br />
+**[[3dy0]] – hSer-A5 + heparin
-[[2jp8]] – hSer-A8 – NMR<br />
+*Serpin A6 see [[Corticosteroid-binding globulin]]
-[[2wxw]] – hSer-A8<br />
-[[2x0b]] – hSer-A8 + renin<br />
-[[2wxx]], [[2wxy]], [[2wy0]] – Ser-A8 – mouse<br />
-[[2wxz]], [[2wy1]] – rSer-A8
-===Ser A10===
+*Serpin A7
-[[3h5c]], [[3f1s]] – hSer-A10 + vitamin K-dependent protein Z
+**[[2riv]] – hSer-A7<br />
+**[[2riw]] – hSer-A7 + thyroxine<br />
+**[[2xn3]] – hSer-A7 + mefenamic acid<br />
+**[[2xn5]] – hSer-A7 + furosemide<br />
+**[[2xn6]], [[2xn7]] – hSer-A7 + thyroxine-fluoresein
-===Ser A12===
+*Serpin A8
-[[4if8]] – hSer-A12<br />
+**[[2jp8]] – hSer-A8 – NMR<br />
+**[[2wxw]] – hSer-A8<br />
+**[[2x0b]] – hSer-A8 + renin<br />
+**[[2wxx]], [[2wxy]], [[2wy0]] – Ser-A8 – mouse<br />
+**[[2wxz]], [[2wy1]] – rSer-A8
-===Ser B1 (leukocyte elastase inhibitor)===
+*Serpin A10
-[[1hle]] – Ser-B1 – horse <br />
+**[[3h5c]], [[3f1s]] – hSer-A10 + vitamin K-dependent protein Z
-[[4ga7]] – hSer-B1 (mutant) <br />
-===Ser B3===
+*Serpin A12
-[[2zv6]] – hSer-B3
+**[[4if8]] – hSer-A12<br />
-===Ser B5 (Maspin)===
+*Serpin B1 (leukocyte elastase inhibitor)
-[[1xqg]], [[1wz9]], [[1xu8]] - hSer-B5<br />
+**[[1hle]] – Ser-B1 – horse <br />
-[[1xqj]] – hSer-B5 (mutant) <br />
+**[[4ga7]] – hSer-B1 (mutant) <br />
-===Ser C1===
+*Serpin B3
-[[Antithrombin]]
+**[[2zv6]] – hSer-B3
-===Ser E1===
+*Serpin B5 (Maspin)
-[[Plasminogen activator inhibitor]]
+**[[1xqg]], [[1wz9]], [[1xu8]] - hSer-B5<br />
+**[[1xqj]] – hSer-B5 (mutant) <br />
-===Ser E2===
+*Serpin C1 see [[Antithrombin]]
-[[4dy0]] – hSer-E2 + heparin
+*Serpin E1 see [[Plasminogen activator inhibitor]]
-===Ser-I1===
+*Serpin E2
-[[3fgq]], [[2f02]], [[3f5n]] – hSer-I1
+**[[4dy0]] – hSer-E2 + heparin
-===Ser K===
+*Serpin-I1
-[[1sek]] – ThSer-K – Tobacco hornworm
+**[[3fgq]], [[2f02]], [[3f5n]] – hSer-I1
-===Ser 1===
+*Serpin K
-[[1k9o]] – ThSer-1 (mutant) + trypsin II<br />
+**[[1sek]] – ThSer-K – Tobacco hornworm
-[[3le2]] – Ser-1 – ''Arabidopsis thaliana''
-===Ser 2===
+*Serpin 1
-[[1m93]] – Ser-2 – Cowpox virus<br />
+**[[1k9o]] – ThSer-1 (mutant) + trypsin II<br />
-[[3nda]] – Ser-2 – Sheep tick<br />
+**[[3le2]] – Ser-1 – ''Arabidopsis thaliana''
-[[3pzf]] – Ser-2 – malaria mosquito
+*Serpin 2
+**[[1m93]] – Ser-2 – Cowpox virus<br />
+**[[3nda]] – Ser-2 – Sheep tick<br />
+**[[3pzf]] – Ser-2 – malaria mosquito
+}}
-</StructureSection>
 [[Category:Topic Page]]

Serpin: Difference between revisions

Revision as of 13:03, 10 December 2014

3D structures of serpin3D structures of serpin

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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