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[[Image: | ==Crystal structure of Tudor domain of human Histone-lysine N-methyltransferase SETDB1== | ||
<StructureSection load='3dlm' size='340' side='right' caption='[[3dlm]], [[Resolution|resolution]] 1.77Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3dlm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DLM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3DLM FirstGlance]. <br> | |||
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SETDB1, KIAA0067, KMT1E ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone-lysine_N-methyltransferase Histone-lysine N-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.43 2.1.1.43] </span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dlm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dlm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3dlm RCSB], [http://www.ebi.ac.uk/pdbsum/3dlm PDBsum]</span></td></tr> | |||
</table> | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dl/3dlm_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | |||
*[[Histone methyltransferase|Histone methyltransferase]] | |||
__TOC__ | |||
</StructureSection> | |||
[[ | |||
[[Category: Histone-lysine N-methyltransferase]] | [[Category: Histone-lysine N-methyltransferase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Amaya, M F | [[Category: Amaya, M F]] | ||
[[Category: Arrowsmith, C H | [[Category: Arrowsmith, C H]] | ||
[[Category: Bochkarev, A | [[Category: Bochkarev, A]] | ||
[[Category: Bountra, C | [[Category: Bountra, C]] | ||
[[Category: Dombrovski, L | [[Category: Dombrovski, L]] | ||
[[Category: Edwards, A M | [[Category: Edwards, A M]] | ||
[[Category: Loppnau, P | [[Category: Loppnau, P]] | ||
[[Category: Min, J | [[Category: Min, J]] | ||
[[Category: | [[Category: Structural genomic]] | ||
[[Category: Weigelt, J | [[Category: Weigelt, J]] | ||
[[Category: Wu, H | [[Category: Wu, H]] | ||
[[Category: Chromatin regulator]] | [[Category: Chromatin regulator]] | ||
[[Category: Chromosomal protein]] | [[Category: Chromosomal protein]] | ||
Line 30: | Line 44: | ||
[[Category: Setdb1_human]] | [[Category: Setdb1_human]] | ||
[[Category: Sgc]] | [[Category: Sgc]] | ||
[[Category: Transcription]] | [[Category: Transcription]] | ||
[[Category: Transcription regulation]] | [[Category: Transcription regulation]] | ||
[[Category: Transferase]] | [[Category: Transferase]] |
Revision as of 11:01, 12 November 2014
Crystal structure of Tudor domain of human Histone-lysine N-methyltransferase SETDB1Crystal structure of Tudor domain of human Histone-lysine N-methyltransferase SETDB1
Structural highlights
Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
|
Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Histone-lysine N-methyltransferase
- Homo sapiens
- Amaya, M F
- Arrowsmith, C H
- Bochkarev, A
- Bountra, C
- Dombrovski, L
- Edwards, A M
- Loppnau, P
- Min, J
- Structural genomic
- Weigelt, J
- Wu, H
- Chromatin regulator
- Chromosomal protein
- Histone-lysine n-methyltransferase
- Nucleus
- Phosphoprotein
- Repressor
- S-adenosyl-l-methionine
- Setdb1 human
- Sgc
- Transcription
- Transcription regulation
- Transferase