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==Crystal structure of human CYP7A1 in complex with 7-ketocholesterol== | |||
<StructureSection load='3v8d' size='340' side='right' caption='[[3v8d]], [[Resolution|resolution]] 1.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3v8d]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V8D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3V8D FirstGlance]. <br> | |||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0GV:(3BETA,8ALPHA,9BETA)-3-HYDROXYCHOLEST-5-EN-7-ONE'>0GV</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene><br> | |||
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CYP7A1, CYP7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | |||
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cholesterol_7-alpha-monooxygenase Cholesterol 7-alpha-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.13.17 1.14.13.17] </span></td></tr> | |||
== | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3v8d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v8d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3v8d RCSB], [http://www.ebi.ac.uk/pdbsum/3v8d PDBsum]</span></td></tr> | ||
[[3v8d]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | <table> | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Cholesterol 7-alpha-monooxygenase]] | [[Category: Cholesterol 7-alpha-monooxygenase]] | ||
[[Category: | [[Category: Human]] | ||
[[Category: Arrowsmith, C H.]] | [[Category: Arrowsmith, C H.]] | ||
[[Category: Bountra, C.]] | [[Category: Bountra, C.]] |
Revision as of 10:13, 11 June 2014
Crystal structure of human CYP7A1 in complex with 7-ketocholesterolCrystal structure of human CYP7A1 in complex with 7-ketocholesterol
Structural highlights
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