Atlastin: Difference between revisions

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New page: <StructureSection load='3q5e' size='340' side='right' caption='Structure of human atlastin cytoplasmic domain complex with GDP (PDB code 3q5e).' scene=''> == Function == '''Atlastin...
 
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<StructureSection load='4ido' size='340' side='right' caption='Structure of human atlastin cytoplasmic domain complex with GDP (PDB code [[4ido]]).' scene=''>
<StructureSection load='3q5e' size='340' side='right' caption='Structure of human atlastin cytoplasmic domain complex with GDP (PDB code [[3q5e]]).' scene=''>


== Function ==
== Function ==

Revision as of 12:27, 10 June 2014

<StructureSection load='4ido' size='340' side='right' caption='Structure of human atlastin cytoplasmic domain complex with GDP (PDB code 4ido).' scene=>

FunctionFunction

Atlastin (ATN) is a GTPase and a Golgi body transmembrane protein. ATN was shown to be required in membrane fusion and ER formation in Drosophila melanogaster.

DiseaseDisease

Defects in the ATN gene are a cause of spastic paraplegia type 3.

RelevanceRelevance

Structural highlightsStructural highlights

3D structures of atlastin3D structures of atlastin

Updated on 10-June-2014

3q5d, 3q5e, 3qnu, 3qof – hATN cytoplasmic domain + GDP – human
4idn – hATN cytoplasmic domain + GNP
4idp – hATN cytoplasmic domain (mutant) + GNP
4ido – hATN cytoplasmic domain + GDP + AlF4
4idq – hATN cytoplasmic domain (mutant) + GDP + AlF4


ReferencesReferences

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky