Gcn4: Difference between revisions
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
[[2zta]], [[1w5i]], [[2b1f]], [[2b22]], [[2ag3]], [[2oxj]], [[2oxk]], [[2r2v]] – yGcn4 - yeast <br /> | [[2zta]], [[1w5i]], [[2b1f]], [[2b22]], [[2ag3]], [[2oxj]], [[2oxk]], [[2r2v]], [[4c46]] – yGcn4 - yeast <br /> | ||
[[2ovn]], [[2l56]] – yGcn4 - NMR<br /> | [[2ovn]], [[2l56]] – yGcn4 - NMR<br /> | ||
[[1u2u]] – yGcn4 dimer - NMR<br /> | [[1u2u]] – yGcn4 dimer - NMR<br /> | ||
[[4dmd]], [[1kd8]], [[1kd9]], [[1kdd]] – yGcn4 dimer <br /> | [[4dmd]], [[1kd8]], [[1kd9]], [[1kdd]], [[4hu5]], [[4hu6]] – yGcn4 dimer <br /> | ||
[[4dme]] – yGcn4 trimer <br /> | [[4dme]] – yGcn4 trimer <br /> | ||
[[3ck4]], [[3crp]], [[2ipz]] – yGcn4 tetramer <br /> | [[3ck4]], [[3crp]], [[2ipz]] – yGcn4 tetramer <br /> | ||
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[[1c94]] – yGcn4 retro<br /> | [[1c94]] – yGcn4 retro<br /> | ||
[[1ysa]], [[1dgc]], [[2dgc]] – yGcn4 dimer + DNA <br /> | [[1ysa]], [[1dgc]], [[2dgc]] – yGcn4 dimer + DNA <br /> | ||
[[2lpb]] – yGcn4 + mediator of RNA polymerase II<br /> | |||
===Gcn4 fusion proteins=== | ===Gcn4 fusion proteins=== | ||
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[[3i5c]] – yGcn4/WSPR response regulator<br /> | [[3i5c]] – yGcn4/WSPR response regulator<br /> | ||
[[3p8m]] – yGcn4/dynein<br /> | [[3p8m]] – yGcn4/dynein<br /> | ||
[[4g2k]] – yGcn4/virus envelope glycoprotein<br /> | [[4g2k]], [[1env]], [[1fav]], [[1gcl]], [[2q5u]], [[2q7c]], [[3g9r]] – yGcn4/virus envelope glycoprotein<br /> | ||
[[1kql]], [[2z5i]] – yGcn4/α-tropomyosin<br /> | |||
[[2z5h]] – yGcn4/α-tropomyosin + troponin T<br /> | |||
[[3bas]], [[3bat]] – yGcn4/myosin<br /> | |||
[[1wvl]], [[2d3e]], [[2efr]], [[2efs]], [[2g9j]] – yGcn4/SAC7D + DNA<br | |||
[[4m8m]] – yGcn4/plexin<br />/> | |||
[[1ld4]] – yGcn4 + virus coat protein + virus spike glycoprotein<br /> | [[1ld4]] – yGcn4 + virus coat protein + virus spike glycoprotein<br /> | ||
[[Category:Topic Page]] | |||
Revision as of 11:03, 10 March 2014
Gcn4 is a yeast transcriptional activator. It belongs to a large family of eukaryotic transcription factors including Fos, Jun and CREB. All family members have a DNA recognition motif consists of a coiled-coil dimerization element, the leucine-zipper, and an adjoining basic region, which mediates DNA binding. This basic region is largely unstructured in the absence of DNA, addition of DNA containing a Gcn4 binding site induce the transition of this region from unstructured to α-helical. See also Intrinsically Disordered Protein.
3D Structures of Gcn43D Structures of Gcn4
Updated on 10-March-2014
2zta, 1w5i, 2b1f, 2b22, 2ag3, 2oxj, 2oxk, 2r2v, 4c46 – yGcn4 - yeast
2ovn, 2l56 – yGcn4 - NMR
1u2u – yGcn4 dimer - NMR
4dmd, 1kd8, 1kd9, 1kdd, 4hu5, 4hu6 – yGcn4 dimer
4dme – yGcn4 trimer
3ck4, 3crp, 2ipz – yGcn4 tetramer
1gcl, 1swi, 1ce9, 1w5g, 1w5h, 1w5j, 1w5k, 1w5l, 1unt, 1unu, 1unv, 1unw, 1unx, 1uny, 1unz, 1uo0, 1uo1, 1uo2, 1uo3, 1uo4, 1uo5, 1u9f, 1u9g, 1u9h, 2bni, 2cce, 2ccf, 2ccn, 2ahp, 2hy6, 3i1g, 2wpy, 2wpz, 2wq0, 2wq1, 2wq2, 2wq3, 3k7z, 3gjp, 3m48 – yGcn4 (mutant)
1zii, 1zik, 1zil – yGcn4 dimer (mutant)
2o7h, 1gcm, 1zij, 1zim, 1piq, 1ij0, 1ij1, 1ij2, 1ij3, 1rb4, 1rb5, 1rb6 – yGcn4 trimer (mutant)
2nrn – yGcn4 tetramer (mutant)
1fmh – yGcn4 dimer (mutant) - NMR
1c94 – yGcn4 retro
1ysa, 1dgc, 2dgc – yGcn4 dimer + DNA
2lpb – yGcn4 + mediator of RNA polymerase II
Gcn4 fusion proteinsGcn4 fusion proteins
1gk6 – yGcn4/vimentin
2wg5 – yGcn4/proteasome-activating nucleotidase
2wg6 – yGcn4 (mutant)/proteasome-activating nucleotidase
2yny, 2ynz, 2yo0, 2yo1, 2yo2, 2yo3, 3zmf – yGcn4/inner membrane protein
3i5c – yGcn4/WSPR response regulator
3p8m – yGcn4/dynein
4g2k, 1env, 1fav, 1gcl, 2q5u, 2q7c, 3g9r – yGcn4/virus envelope glycoprotein
1kql, 2z5i – yGcn4/α-tropomyosin
2z5h – yGcn4/α-tropomyosin + troponin T
3bas, 3bat – yGcn4/myosin
1wvl, 2d3e, 2efr, 2efs, 2g9j – yGcn4/SAC7D + DNA<br
4m8m – yGcn4/plexin
/>
1ld4 – yGcn4 + virus coat protein + virus spike glycoprotein