4ivt: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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-'''Unreleased structure'''
+{{STRUCTURE_4ivt|  PDB=4ivt  |  SCENE=  }}
+===Crystal structure of BACE1 with its inhibitor===
+{{ABSTRACT_PUBMED_23681056}}
-The entry 4ivt is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/BACE1_HUMAN BACE1_HUMAN]] Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.<ref>PMID:10677483</ref> <ref>PMID:20354142</ref>
-Authors: Chen, T.T., Li, L., Chen, W.Y., Xu, Y.C.
+==About this Structure==
+[[4ivt]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IVT OCA].
-Description: Crystal structure of BACE1 with its inhibitor
+==Reference==
+<ref group="xtra">PMID:023681056</ref><references group="xtra"/><references/>
+[[Category: Memapsin 2]]
+[[Category: Chen, T T.]]
+[[Category: Chen, W Y.]]
+[[Category: Li, L.]]
+[[Category: Xu, Y C.]]
+[[Category: Hydrolase]]
+[[Category: Hydrolase-hydrolase inhibitor complex]]