Hormone: Difference between revisions

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[[Beta-2 Adrenergic Receptor]]<br />
[[Beta-2 Adrenergic Receptor]]<br />
The human β2 adrenergic receptor bound to a G-protein ([[3sn6]]) and [[hormone]] analog is featured in an image on the right, and additional structures are on the [[Adrenergic receptor|Adrenergic receptor page]]. <br />
The human β2 adrenergic receptor bound to a G-protein ([[3sn6]]) and [[hormone]] analog is featured in an image on the right, and additional structures are on the [[Adrenergic receptor|Adrenergic receptor page]]. <br />
{{Template:GPCR3sn6}}


===Angiotensinogen===
===Angiotensinogen===
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[[1hcn]] - Chorionic Gonadotropin – human<br />
[[1hcn]] - Chorionic Gonadotropin – human<br />
[[1hd4]] - Alpha-subunit of Chorionic Gonadotropin – human<br />
[[1hd4]] - Alpha-subunit of Chorionic Gonadotropin – human<br />
===Estrogen-related receptor===
Estrogen-related recepto – human and others, see [[Estrogen-related_receptor#3D_structures_of_estrogen-related_receptor|Estrogen-related receptor structures]]<br />
===Farnesoid X Receptor ===
[[3olf]], [[3omk]], [[3omm]], [[3oof]], [[3ook]], [[3okh]], [[3oki]] - Farnesoid X Receptor  – human<br />


===Follicle-Stimulating Hormone===
===Follicle-Stimulating Hormone===
Line 88: Line 95:
[[2xn3]], [[2xn5]], [[2xn6]], [[2xn7]] - Thyroxine-binding Globulin  – human<br />
[[2xn3]], [[2xn5]], [[2xn6]], [[2xn7]] - Thyroxine-binding Globulin  – human<br />


===Farnesoid X Receptor ===
[[3olf]], [[3omk]], [[3omm]], [[3oof]], [[3ook]], [[3okh]], [[3oki]] - Farnesoid X Receptor  – human<br />


===PACAP/glucagon family of peptide hormones===
===PACAP/glucagon family of peptide hormones===
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[[2jod]] -  Pituitary adenylate cyclase-activating polypeptide (residues 6'-38') complexed to the extracellular  domain of the human splice variant hPAC1-RS determined by NMR - human<br />
[[2jod]] -  Pituitary adenylate cyclase-activating polypeptide (residues 6'-38') complexed to the extracellular  domain of the human splice variant hPAC1-RS determined by NMR - human<br />


===Estrogen-related receptor===
 
Estrogen-related recepto – human and others, see [[Estrogen-related_receptor#3D_structures_of_estrogen-related_receptor|Estrogen-related receptor structures]]<br />




Revision as of 02:52, 16 December 2012

In the field of modern endocrinology, a hormone is any substance, generated either externally or internally, that operates via a receptor at the cellular level, which conveys to to the cell a message to stop, start, or modulate a cellular process.

Guide to Proteopedia Pages Concerning Hormones and their ReceptorsGuide to Proteopedia Pages Concerning Hormones and their Receptors


To view automatically seeded indices concerning Hormone, see:


Additional 3D Structures of Hormones and Hormone Receptors and Related MoleculesAdditional 3D Structures of Hormones and Hormone Receptors and Related Molecules

AdrenalineAdrenaline

Beta-2 Adrenergic Receptor
The human β2 adrenergic receptor bound to a G-protein (3sn6) and hormone analog is featured in an image on the right, and additional structures are on the Adrenergic receptor page.

 
Drag the structure with the mouse to rotate
An activated G protein-coupled receptor (human β-2 adrenergic receptor in blue ) in a complex with a heterotrimeric G protein (3 subunits:reddish to orange-brown) and hormone (gold) (3sn6), resolution 3.2Å. The boundaries of the membrane in which the GPCR sits are represented in light green.



AngiotensinogenAngiotensinogen

2wxw, 2wxx, 2wxy, 2wxz, 2wy0, 2wy1, 2x0b - Angiotensinogen – human, rat, mouse

Chorionic GonadotropinChorionic Gonadotropin

1hrp - Chorionic Gonadotropin – human
1hcn - Chorionic Gonadotropin – human
1hd4 - Alpha-subunit of Chorionic Gonadotropin – human

Estrogen-related receptorEstrogen-related receptor

Estrogen-related recepto – human and others, see Estrogen-related receptor structures

Farnesoid X ReceptorFarnesoid X Receptor

3olf, 3omk, 3omm, 3oof, 3ook, 3okh, 3oki - Farnesoid X Receptor – human

Follicle-Stimulating HormoneFollicle-Stimulating Hormone

Drag the structure with the mouse to rotate
FSH binding to the leucine-rich domain of Follicle Stimulating Hormone Receptor (1fl7 morphing to 1xwd, resolution 2.92Å)


1fl7 - Follicle-Stimulating Hormone – human
1xwd - Human Follicle Stimulating Hormone complexed with its Receptor – human

GlucocorticoidGlucocorticoid

3mne, 3mno, 3mnp - Glucocorticoid Receptor Ligand-binding Domain – human

Glucose-dependent Insulinotropic PolypeptideGlucose-dependent Insulinotropic Polypeptide

Glucose-dependent Insulinotropic Polypeptide Receptor

Growth HormoneGrowth Hormone

3hhr - Growth Hormone complexed with the extracellular portion of its receptor - human
1hwh - Growth Hormone Mutant G120R complexed with the extracellular portion of its receptor - human
1bp3 - Growth Hormone complexed with the prolactin receptor - human
3mjg, 3mjk - Platelet-derived Growth Factor/Propeptide Complex and a Platelet-Derived Growth Factor/Receptor Complex – human
Vascular Endothelial Growth Factor – human and others, see Vascular Endothelial Growth Factor Structures
Vascular Endothelial Growth Factor Receptor – human, see Vascular Endothelial Growth Factor Receptor Structures
2xdg - Extracellular Domain of Human Growth Hormone Releasing Hormone Receptor – human

InsulinInsulin

3ir0 , 1mso , 1trz , 2qiu , 2r34, 2r35 , 2r36, 3ilg, 2kjj , 2kju - Insulin – human
3nw5, 3nw6, 3nw7 - insulin-like growth factor 1 receptor – human
3loh, 2dtg - insulin receptor ectodomain – human
Glucose-dependent Insulinotropic Polypeptide Receptor

ProgesteroneProgesterone

3hq5,3g8n, 3g8o, 3hq5 - Progesterone – human

Thyroid-Stimulating hormoneThyroid-Stimulating hormone

3g04 - TSH receptor in complex with a thyroid-stimulating autoantibody – human

Thyroid hormoneThyroid hormone

2nll - DNA-Binding domain in complex with an inverted repeat class of thyroid response element– rat
1xzx

ThyroxineThyroxine

2xn3, 2xn5, 2xn6, 2xn7 - Thyroxine-binding Globulin – human


PACAP/glucagon family of peptide hormonesPACAP/glucagon family of peptide hormones

3n94 - PAC1R, receptor of pituitary adenylate cyclase activating polypeptide, is a case of a crystal structure disagreeing with the NMR structure 2jod and vice versa
2jod - Pituitary adenylate cyclase-activating polypeptide (residues 6'-38') complexed to the extracellular domain of the human splice variant hPAC1-RS determined by NMR - human



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See AlsoSee Also


External ResourcesExternal Resources

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Wayne Decatur, Tomas Klumpler, Joel L. Sussman, Michal Harel, Alexander Berchansky
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