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| Line 12: |
Line 12: |
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| |
|
|
| |
|
| Sequence:
| |
| 10 20 30 40 50 60
| |
| MRTTPTFPTK TFKPTAMALA VATTLSACLG GGGGGTSAPD FNAGGTGIGS NSRATTAKSA
| |
|
| |
|
| 70 80 90 100 110 120
| |
| AVSYAGIKNE MCKDRSMLCA GRDDVAVTDR DAKINAPPPP NLHTGDFPNP NDAYKNLINL
| |
|
| |
| 130 140 150 160 170 180
| |
| KPAIEAGYTG RGVEVGIVDT GESVGSISFP ELYGRKEHGY NENYKNYTAY MRKEAPEDGG
| |
|
| |
| 190 200 210 220 230 240
| |
| GKDIEASFDD EAVIETEAKP TDIRHVKEIG HIDLVSHIIG GRSVDGRPAG GIAPDATLHI
| |
|
| |
| 250 260 270 280 290 300
| |
| MNTNDGTKNE MMVAAIRNAW VKLGERGVRI VNNSFGTTSR AGTADLFQIA NSEEQYRQAL
| |
|
| |
| 310 320 330 340 350 360
| |
| LDYSGGDKTD EGIRLMQQSD YGNLSYHIRN KNMLFIFSTG NDAQAQPNTY ALLPFYEKDA
| |
|
| |
| 370 380 390 400 410 420
| |
| QKGIITVAGV DRSGEKFKRE MYGEPGTEPL EYGSNHCGIT AMWCLSAPYE ASVRFTRTNP
| |
|
| |
| 430 440 450 460 470 480
| |
| IQIAGTSFSA PIVTGTAALL LQKYPWMSND NLRTTLLTTA QDIGAVGVDS KFGWGLLDAG
| |
|
| |
| 490 500 510 520 530 540
| |
| KAMNGPASFP FGDFTADTKG TSDIAYSFRN DISGTGGLIK KGGSQLQLHG NNTYTGKTII
| |
|
| |
| 550 560 570 580 590 600
| |
| EGGSLVLYGN NKSDMRVETK GALIYNGAAS GGSLNSDGIV YLADTDQSGA NETVHIKGSL
| |
|
| |
| 610 620 630 640 650 660
| |
| QLDGKGTLYT RLGKLLKVDG TAIIGGKLYM SARGKGAGYL NSTGRRVPFL SAAKIGQDYS
| |
|
| |
| 670 680 690 700 710 720
| |
| FFTNIETDGG LLASLDSVEK TAGSEGDTLS YYVRRGNAAR TASAAAHSAP AGLKHAVEQG
| |
|
| |
| 730 740 750 760 770 780
| |
| GSNLENLMVE LDASESSATP ETVETAAADR TDMPGIRPYG ATFRAAAAVQ HANAADGVRI
| |
|
| |
| 790 800 810 820 830 840
| |
| FNSLAATVYA DSTAAHADMQ GRRLKAVSDG LDHNGTGLRV IAQTQQDGGT WEQGGVEGKM
| |
|
| |
| 850 860 870 880 890 900
| |
| RGSTQTVGIA AKTGENTTAA ATLGMGRSTW SENSANAKTD SISLFAGIRH DAGDIGYLKG
| |
|
| |
| 910 920 930 940 950 960
| |
| LFSYGRYKNS ISRSTGADEH AEGSVNGTLM QLGALGGVNV PFAATGDLTV EGGLRYDLLK
| |
|
| |
| 970 980 990 1000 1010 1020
| |
| QDAFAEKGSA LGWSGNSLTE GTLVGLAGLK LSQPLSDKAV LFATAGVERD LNGRDYTVTG
| |
|
| |
| 1030 1040 1050 1060 1070 1080
| |
| GFTGATAATG KTGARNMPHT RLVAGLGADV EFGNGWNGLA RYSYAGSKQY GNHSGRVGVG
| |
|
| |
|
| |
| YRF
| |
| == History == | | == History == |
|
| |
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| Line 95: |
Line 39: |
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| |
|
| ==Structure== | | ==Structure== |
| | |
| | ===Beta Barrel=== |
| | |
| | The unique structure that makes this pore is able to allow for transportation in and out of the gram-negative cell is what is called a beta barrel. This beta barrel is created with 12 anti-parellel beta-pleated sheets that have wrapped around creating anti-parellel interaction between sheet one and sheet 12. This creates a tube structure that transcends through the membrane of a cell creating a new environment that allows for polar molecules to move through the cell membrane and cell wall when they would have otherwise been stopped by the hydrophobic center of peptidoglycan. The start and end of the beta barrel is on the periplasm side of the membrane and after a short tight turn T0 becomes the alpha-helix which has its n-terminus side facing outward toward extracellular material. |
|
| |
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| === Alpha Helix === | | === Alpha Helix === |