Hormone

In the field of modern endocrinology, a hormone is any substance, generated either externally or internally, that operates via a receptor at the cellular level, which conveys to to the cell a message to stop, start, or modulate a cellular process.

Guide to Proteopedia Pages Concerning Hormones and their ReceptorsGuide to Proteopedia Pages Concerning Hormones and their Receptors

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FSH binding to the leucine-rich domain of Follicle Stimulating Hormone Receptor (1fl7 morphing to 1xwd, resolution 2.92Å)

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Articles in Proteopedia concerning Hormone include:

• Human Follicle-Stimulating Hormone Complexed with its Receptor
• Estrogen-related receptor
• Leucine-rich repeat proteins
• Vascular Endothelial Growth Factor
• Vascular Endothelial Growth Factor Receptor
• Receiver domain of sensor histidine kinase CKI1

To view automatically seeded indices concerning Hormone, see:

• Hormone
• Hormone Receptor
• Steroid receptor
• Steroid hormone receptor

Additional 3D Structures of Hormones and Hormone Receptors and Related MoleculesAdditional 3D Structures of Hormones and Hormone Receptors and Related Molecules

AngiotensinogenAngiotensinogen

2wxw, 2wxx, 2wxy, 2wxz, 2wy0, 2wy1, 2x0b - Angiotensinogen – human, rat, mouse

Chorionic GonadotropinChorionic Gonadotropin

1hrp - Chorionic Gonadotropin – human
1hcn - Chorionic Gonadotropin – human
1hd4 - Alpha-subunit of Chorionic Gonadotropin – human

Follicle-Stimulating HormoneFollicle-Stimulating Hormone

1fl7 - Follicle-Stimulating Hormone – human
1xwd - Human Follicle Stimulating Hormone complexed with its Receptor – human

GlucocorticoidGlucocorticoid

3mne, 3mno, 3mnp - Glucocorticoid Receptor Ligand-binding Domain – human

Glucose-dependent Insulinotropic PolypeptideGlucose-dependent Insulinotropic Polypeptide

Glucose-dependent Insulinotropic Polypeptide Receptor

Growth HormoneGrowth Hormone

3hhr - Growth Hormone complexed with the extracellular portion of its receptor - human
1hwh - Growth Hormone Mutant G120R complexed with the extracellular portion of its receptor - human
1bp3 - Growth Hormone complexed with the prolactin receptor - human
3mjg, 3mjk - Platelet-derived Growth Factor/Propeptide Complex and a Platelet-Derived Growth Factor/Receptor Complex – human
Vascular Endothelial Growth Factor – human and others, see Vascular Endothelial Growth Factor Structures
Vascular Endothelial Growth Factor Receptor – human, see Vascular Endothelial Growth Factor Receptor Structures
2xdg - Extracellular Domain of Human Growth Hormone Releasing Hormone Receptor – human

InsulinInsulin

3ir0 , 1mso , 1trz , 2qiu , 2r34, 2r35 , 2r36, 3ilg, 2kjj , 2kju - Insulin – human
3nw5, 3nw6, 3nw7 - insulin-like growth factor 1 receptor – human
3loh, 2dtg - insulin receptor ectodomain – human
Glucose-dependent Insulinotropic Polypeptide Receptor

ProgesteroneProgesterone

3hq5,3g8n, 3g8o, 3hq5 - Progesterone – human

Thyroid-Stimulating hormoneThyroid-Stimulating hormone

3g04 - TSH receptor in complex with a thyroid-stimulating autoantibody – human

Thyroid hormoneThyroid hormone

2nll - DNA-Binding domain in complex with an inverted repeat class of thyroid response element– rat
1xzx

ThyroxineThyroxine

2xn3, 2xn5, 2xn6, 2xn7 - Thyroxine-binding Globulin – human

Farnesoid X ReceptorFarnesoid X Receptor

3olf, 3omk, 3omm, 3oof, 3ook, 3okh, 3oki - Farnesoid X Receptor – human

PACAP/glucagon family of peptide hormonesPACAP/glucagon family of peptide hormones

3n94 - PAC1R, receptor of pituitary adenylate cyclase activating polypeptide, is a case of a crystal structure disagreeing with the NMR structure 2jod and vice versa
2jod - Pituitary adenylate cyclase-activating polypeptide (residues 6'-38') complexed to the extracellular domain of the human splice variant hPAC1-RS determined by NMR - human

Estrogen-related receptorEstrogen-related receptor

Estrogen-related recepto – human and others, see Estrogen-related receptor structures

ADD 3dzu

See AlsoSee Also

• Cancer
• Membrane proteins
• G protein-coupled receptors

External ResourcesExternal Resources

• Sequence-Structure-Function-Analysis of Glycoprotein Hormone Receptors
• GRIS: Glycoprotein-hormone Receptors Information System
• The GPCR-SSFE Database: A Homology Model Resource for G-Protein Coupled Receptors
• The feature on Growth Hormone by Shuchismita Dutta and David S. Goodsell for the April 2004 RCSB PDB Molecule of the Month.
• NeuroPedia, a neuropeptide database and spectral library