1jk3: Difference between revisions

Revision as of 19:03, 27 July 2012

Ligands:

, ,

Activity:

Macrophage elastase, with EC number 3.4.24.65

Structural annotation:
Resources:	CATH : 1Jk3A00 InterPro : Ipr006025, Ipr000585, Ipr001818, Ipr006026, Ipr002477 Pfam : PF00413 SCOP : d1jk3a_ UniProt : P39900

Functional annotation:
Cellular component:	proteinaceous extracellular matrix
Biological process:	metabolic process cell motility proteolysis
Molecular function:	peptidase activity zinc ion binding catalytic activity hydrolase activity calcium ion binding metallopeptidase activity metal ion binding macrophage elastase activity metalloendopeptidase activity

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, PDBsum, RCSB

Coordinates:

save as pdb, mmCIF, xml

1jk3 is a 1 chain structure of Elastase and Matrix metalloproteinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

↑ Lang R, Kocourek A, Braun M, Tschesche H, Huber R, Bode W, Maskos K. Substrate specificity determinants of human macrophage elastase (MMP-12) based on the 1.1 A crystal structure. J Mol Biol. 2001 Sep 28;312(4):731-42. PMID:11575928 doi:10.1006/jmbi.2001.4954

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