2qlq: Difference between revisions
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[[Image:2qlq.png|left|200px]] | [[Image:2qlq.png|left|200px]] | ||
{{STRUCTURE_2qlq| PDB=2qlq | SCENE= }} | {{STRUCTURE_2qlq| PDB=2qlq | SCENE= }} | ||
===Crystal structure of SRC kinase domain with covalent inhibitor RL3=== | ===Crystal structure of SRC kinase domain with covalent inhibitor RL3=== | ||
{{ABSTRACT_PUBMED_18316192}} | {{ABSTRACT_PUBMED_18316192}} | ||
==About this Structure== | ==About this Structure== | ||
[[2qlq]] is a 2 chain structure of [[Proto-oncogene tyrosine-protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QLQ OCA]. | |||
==See Also== | |||
*[[Proto-oncogene tyrosine-protein kinase|Proto-oncogene tyrosine-protein kinase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:018316192</ref><references group="xtra"/> | ||
[[Category: Gallus gallus]] | [[Category: Gallus gallus]] | ||
[[Category: Non-specific protein-tyrosine kinase]] | [[Category: Non-specific protein-tyrosine kinase]] | ||
| Line 30: | Line 21: | ||
[[Category: Rauh, D.]] | [[Category: Rauh, D.]] | ||
[[Category: Rode, H B.]] | [[Category: Rode, H B.]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Drug resistance]] | [[Category: Drug resistance]] | ||
| Line 45: | Line 35: | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Tyrosine-protein kinase]] | [[Category: Tyrosine-protein kinase]] | ||
Revision as of 17:23, 27 July 2012
Crystal structure of SRC kinase domain with covalent inhibitor RL3Crystal structure of SRC kinase domain with covalent inhibitor RL3
Template:ABSTRACT PUBMED 18316192
About this StructureAbout this Structure
2qlq is a 2 chain structure of Proto-oncogene tyrosine-protein kinase with sequence from Gallus gallus. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Michalczyk A, Kluter S, Rode HB, Simard JR, Grutter C, Rabiller M, Rauh D. Structural insights into how irreversible inhibitors can overcome drug resistance in EGFR. Bioorg Med Chem. 2008 Apr 1;16(7):3482-8. Epub 2008 Feb 20. PMID:18316192 doi:10.1016/j.bmc.2008.02.053
Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Pages with broken file links
- Gallus gallus
- Non-specific protein-tyrosine kinase
- Gruetter, C.
- Michalczyk, A.
- Rauh, D.
- Rode, H B.
- Atp-binding
- Drug resistance
- Irreversible inhibitor
- Kovalent inhibitor
- Lipoprotein
- Myristate
- Nucleotide-binding
- Phosphorylation
- Proto-oncogene
- Sh2 domain
- Sh3 domain
- Src kinase domain
- Transferase
- Tyrosine-protein kinase