1o4e: Difference between revisions

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[[Image:1o4e.png|left|200px]]
[[Image:1o4e.png|left|200px]]


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===CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU78299.===
===CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU78299.===


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==Disease==
==About this Structure==
Known disease associated with this structure: Colon cancer, advanced OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190090 190090]]
[[1o4e]] is a 1 chain structure of [[Proto-oncogene tyrosine-protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O4E OCA].


==About this Structure==
==See Also==
1O4E is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O4E OCA].
*[[Proto-oncogene tyrosine-protein kinase|Proto-oncogene tyrosine-protein kinase]]


==Reference==
==Reference==
<ref group="xtra">PMID:14613321</ref><references group="xtra"/>
<ref group="xtra">PMID:014613321</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Transferase]]
[[Category: Transferase]]
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[[Category: Loenze, P.]]
[[Category: Loenze, P.]]
[[Category: Sh2 domain fragment approach]]
[[Category: Sh2 domain fragment approach]]
 
[[Category: Signaling protein]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 00:25:45 2009''

Revision as of 10:41, 27 July 2012

File:1o4e.png

Template:STRUCTURE 1o4e

CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU78299.CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU78299.

Template:ABSTRACT PUBMED 14613321

About this StructureAbout this Structure

1o4e is a 1 chain structure of Proto-oncogene tyrosine-protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. ↑ Lange G, Lesuisse D, Deprez P, Schoot B, Loenze P, Benard D, Marquette JP, Broto P, Sarubbi E, Mandine E. Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J Med Chem. 2003 Nov 20;46(24):5184-95. PMID:14613321 doi:http://dx.doi.org/10.1021/jm020970s

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