8est: Difference between revisions
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[[Image:8est.png|left|200px]] | [[Image:8est.png|left|200px]] | ||
{{STRUCTURE_8est| PDB=8est | SCENE= }} | {{STRUCTURE_8est| PDB=8est | SCENE= }} | ||
===REACTION OF PORCINE PANCREATIC ELASTASE WITH 7-SUBSTITUTED 3-ALKOXY-4-CHLOROISOCOUMARINS: DESIGN OF POTENT INHIBITORS USING THE CRYSTAL STRUCTURE OF THE COMPLEX FORMED WITH 4-CHLORO-3-ETHOXY-7-GUANIDINO-ISOCOUMARIN=== | ===REACTION OF PORCINE PANCREATIC ELASTASE WITH 7-SUBSTITUTED 3-ALKOXY-4-CHLOROISOCOUMARINS: DESIGN OF POTENT INHIBITORS USING THE CRYSTAL STRUCTURE OF THE COMPLEX FORMED WITH 4-CHLORO-3-ETHOXY-7-GUANIDINO-ISOCOUMARIN=== | ||
{{ABSTRACT_PUBMED_2337582}} | {{ABSTRACT_PUBMED_2337582}} | ||
==About this Structure== | ==About this Structure== | ||
[[8est]] is a 1 chain structure of [[Elastase]] with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8EST OCA]. | |||
==See Also== | |||
*[[Elastase|Elastase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:002337582</ref><ref group="xtra">PMID:007604279</ref><references group="xtra"/> | ||
[[Category: Pancreatic elastase]] | [[Category: Pancreatic elastase]] | ||
[[Category: Sus scrofa]] | [[Category: Sus scrofa]] | ||
| Line 29: | Line 20: | ||
[[Category: Powers, J C.]] | [[Category: Powers, J C.]] | ||
[[Category: Radhakrishnan, R.]] | [[Category: Radhakrishnan, R.]] | ||
Revision as of 06:05, 27 July 2012
REACTION OF PORCINE PANCREATIC ELASTASE WITH 7-SUBSTITUTED 3-ALKOXY-4-CHLOROISOCOUMARINS: DESIGN OF POTENT INHIBITORS USING THE CRYSTAL STRUCTURE OF THE COMPLEX FORMED WITH 4-CHLORO-3-ETHOXY-7-GUANIDINO-ISOCOUMARINREACTION OF PORCINE PANCREATIC ELASTASE WITH 7-SUBSTITUTED 3-ALKOXY-4-CHLOROISOCOUMARINS: DESIGN OF POTENT INHIBITORS USING THE CRYSTAL STRUCTURE OF THE COMPLEX FORMED WITH 4-CHLORO-3-ETHOXY-7-GUANIDINO-ISOCOUMARIN
Template:ABSTRACT PUBMED 2337582
About this StructureAbout this Structure
8est is a 1 chain structure of Elastase with sequence from Sus scrofa. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Powers JC, Oleksyszyn J, Narasimhan SL, Kam CM. Reaction of porcine pancreatic elastase with 7-substituted 3-alkoxy-4-chloroisocoumarins: design of potent inhibitors using the crystal structure of the complex formed with 4-chloro-3-ethoxy-7-guanidinoisocoumarin. Biochemistry. 1990 Mar 27;29(12):3108-18. PMID:2337582
- ↑ Peisach E, Casebier D, Gallion SL, Furth P, Petsko GA, Hogan JC Jr, Ringe D. Interaction of a peptidomimetic aminimide inhibitor with elastase. Science. 1995 Jul 7;269(5220):66-9. PMID:7604279