3en4: Difference between revisions
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Revision as of 17:53, 26 July 2012
Targeted polypharmacology: crystal structure of the c-Src kinase domain in complex with PP121, a multitargeted kinase inhibitorTargeted polypharmacology: crystal structure of the c-Src kinase domain in complex with PP121, a multitargeted kinase inhibitor
Template:ABSTRACT PUBMED 18849971
About this StructureAbout this Structure
3en4 is a 2 chain structure of Proto-oncogene tyrosine-protein kinase with sequence from Gallus gallus. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Apsel B, Blair JA, Gonzalez B, Nazif TM, Feldman ME, Aizenstein B, Hoffman R, Williams RL, Shokat KM, Knight ZA. Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases. Nat Chem Biol. 2008 Nov;4(11):691-9. Epub 2008 Oct 12. PMID:18849971 doi:http://dx.doi.org/10.1038/nchembio.117
Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Pages with broken file links
- Gallus gallus
- Non-specific protein-tyrosine kinase
- Apsel, B.
- Blair, J A.
- Knight, Z A.
- Shokat, K M.
- Atp-binding
- Inhibitor
- Kinase
- Kinase-inhibitor complex
- Lipoprotein
- Multitarget
- Myristate
- Nucleotide-binding
- Phosphoinositide
- Phosphoprotein
- Polypharmacology
- Proto-oncogene
- Pyrazolopyrimidine
- Sh2 domain
- Sh3 domain
- Signaling
- Src
- Transferase
- Tyrosine
- Tyrosine-protein kinase