3ui7: Difference between revisions
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[[Image:3ui7.png|left|200px]] | [[Image:3ui7.png|left|200px]] | ||
{{STRUCTURE_3ui7| PDB=3ui7 | SCENE= }} | {{STRUCTURE_3ui7| PDB=3ui7 | SCENE= }} | ||
===Discovery of orally active pyrazoloquinoline as a potent PDE10 inhibitor for the management of schizophrenia=== | ===Discovery of orally active pyrazoloquinoline as a potent PDE10 inhibitor for the management of schizophrenia=== | ||
{{ABSTRACT_PUBMED_22142545}} | {{ABSTRACT_PUBMED_22142545}} | ||
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==See Also== | ==See Also== | ||
*[[Phosphodiesterase]] | *[[Phosphodiesterase|Phosphodiesterase]] | ||
==Reference== | ==Reference== | ||
Revision as of 23:22, 25 July 2012
Discovery of orally active pyrazoloquinoline as a potent PDE10 inhibitor for the management of schizophreniaDiscovery of orally active pyrazoloquinoline as a potent PDE10 inhibitor for the management of schizophrenia
Template:ABSTRACT PUBMED 22142545
About this StructureAbout this Structure
3ui7 is a 2 chain structure of Phosphodiesterase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Yang SW, Smotryski J, McElroy WT, Tan Z, Ho G, Tulshian D, Greenlee WJ, Guzzi M, Zhang X, Mullins D, Xiao L, Hruza A, Chan TM, Rindgen D, Bleickardt C, Hodgson R. Discovery of orally active pyrazoloquinolines as potent PDE10 inhibitors for the management of schizophrenia. Bioorg Med Chem Lett. 2011 Nov 16. PMID:22142545 doi:10.1016/j.bmcl.2011.11.023