Transferrin: Difference between revisions
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{{STRUCTURE_1jnf| PDB=1jnf | SIZE=400| SCENE= |right|CAPTION=Rabbit transferrin [[1jnf]] }} | {{STRUCTURE_1jnf| PDB=1jnf | SIZE=400| SCENE= |right|CAPTION=Rabbit transferrin with Fe, carbonate and chloride [[1jnf]] }} | ||
'''Transferrin''' (TF) is an iron-binding protein. TF delivers iron from absorption centers in the duodendum and white blood cell macrophages to all tissues. TF contains two lobes: at the N and C termini. Ovotransferrin (OTF) is a glycosylated TF of egg white albumen. For details see [[Molecular Playground/Transferrin]]. | '''Transferrin''' (TF) is an iron-binding protein. TF delivers iron from absorption centers in the duodendum and white blood cell macrophages to all tissues. TF contains two lobes: at the N and C termini. Ovotransferrin (OTF) is a glycosylated TF of egg white albumen. For details see [[Molecular Playground/Transferrin]]. | ||
Revision as of 12:17, 31 January 2012
Transferrin (TF) is an iron-binding protein. TF delivers iron from absorption centers in the duodendum and white blood cell macrophages to all tissues. TF contains two lobes: at the N and C termini. Ovotransferrin (OTF) is a glycosylated TF of egg white albumen. For details see Molecular Playground/Transferrin.
3D Structures of Transferrin3D Structures of Transferrin
TransferrinTransferrin
1jnf – rTF - rabbit
1suv – hTF + TF receptor - human
3s9l, 3s9m, 3s9n - hTF (mutant) + TF receptor
1h76 – TF - pig
Transferrin N lobeTransferrin N lobe
1tfd – rTF N terminal
1a8e, 1a8f, 1b3e, 1n84 - hTF N terminal
1dtg, 1d3k, 1d4n, 1fqe, 1fqf, 1jqf, 1n7w, 1n7x, 1oqg, 1oqh, 2o7u, 2o84, 3fgs - hTF N terminal (mutant)
1ryo - hTF N terminal + oxalate
Apo transferrinApo transferrin
1bp5, 1btj - hTF N terminal
2hau, 2hav – hTF (mutant)
OvotransferrinOvotransferrin
1ovt, 1n04 – cOTF - chicken
2d3i – cOTF (Al)
1dot – dOTF - duck
Ovotransferrin N lobeOvotransferrin N lobe
1ovb, 1gv8 – dOTF NII domain
1gvc - dOTF NII domain + nitrilotriacetate
1nnt, 1nft, 1iej – cOTF N terminal
Apo ovotransferrinApo ovotransferrin
1aov – dOTF
1aiv, 1ryx– cOTF
1tfa - cOTF N terminal
1iq7 - cOTF C terminal
1lfc – OTF residues 17-41 – bovine - NMR