3ui7: Difference between revisions
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[[Image:3ui7.png|left|200px]] | |||
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{{STRUCTURE_3ui7| PDB=3ui7 | SCENE= }} | |||
===Discovery of orally active pyrazoloquinoline as a potent PDE10 inhibitor for the management of schizophrenia=== | |||
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{{ABSTRACT_PUBMED_22142545}} | |||
==About this Structure== | |||
[[3ui7]] is a 2 chain structure of [[Phosphodiesterase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UI7 OCA]. | |||
==See Also== | |||
*[[Phosphodiesterase]] | |||
==Reference== | |||
<ref group="xtra">PMID:022142545</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Greenlee, W J.]] | |||
[[Category: Ho, G.]] | |||
[[Category: Hodgson, R.]] | |||
[[Category: Hruza, A.]] | |||
[[Category: Mcelroy, W.]] | |||
[[Category: Smotryski, J.]] | |||
[[Category: Tulshian, D.]] | |||
[[Category: Xiao, L.]] | |||
[[Category: Yang, S.]] | |||
[[Category: Hydrolase]] | |||
[[Category: Hydrolase-hydrolase inhibitor complex]] | |||
[[Category: Inhibitor complex]] | |||
[[Category: Mg binding]] | |||
[[Category: Zn binding]] | |||
Revision as of 08:38, 11 January 2012
Discovery of orally active pyrazoloquinoline as a potent PDE10 inhibitor for the management of schizophreniaDiscovery of orally active pyrazoloquinoline as a potent PDE10 inhibitor for the management of schizophrenia
Template:ABSTRACT PUBMED 22142545
About this StructureAbout this Structure
3ui7 is a 2 chain structure of Phosphodiesterase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Yang SW, Smotryski J, McElroy WT, Tan Z, Ho G, Tulshian D, Greenlee WJ, Guzzi M, Zhang X, Mullins D, Xiao L, Hruza A, Chan TM, Rindgen D, Bleickardt C, Hodgson R. Discovery of orally active pyrazoloquinolines as potent PDE10 inhibitors for the management of schizophrenia. Bioorg Med Chem Lett. 2011 Nov 16. PMID:22142545 doi:10.1016/j.bmcl.2011.11.023