Complexin: Difference between revisions
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'''Complexin''' (CPLX) is the | '''Complexin''' (CPLX) is the protein which binds the SNARE protein complex with high affinity. CPLX acts as both inhibitor and facilitator of vescicle fusion and neurotransmitter release at the synapse. CPLX clamps SNARE complexes to prevent vescicle fusion while in another conformation it releases the SNARE complex allowing fusion. | ||
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Revision as of 10:29, 24 November 2011
Complexin (CPLX) is the protein which binds the SNARE protein complex with high affinity. CPLX acts as both inhibitor and facilitator of vescicle fusion and neurotransmitter release at the synapse. CPLX clamps SNARE complexes to prevent vescicle fusion while in another conformation it releases the SNARE complex allowing fusion.
3D structures of complexin3D structures of complexin
1kil – CPLX + SNARE – rat