Fibrinogen: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

@@ Line 3: / Line 3: @@
 <applet load='3hus2.pdb' size='300' frame='true' align='right' scene="Fibrinogen/Fibrinogen_starting_scene/2" caption= 'Crystal structure of fibrinogen fragment D with the peptide ligand Gly-Pro-Arg-Pro-amide, [[3hus]]' />
+'''Fibrinogen''' is a glycoprotein found in the blood that is converted into fibrin during blood coagulation. Fibrinogen is cleaved by another protein, [[thrombin]], exposing Knobs A & B to form fibrin. It is this fibrin that is linked to clotting factors like factor XIII which form clots to prevent excessive bleeding from wounds sustained.
-'''3D Structure of Fibrinogen''' <br />
-The image at the left is a Crystal Structure of a Fibrinogen Fragment with the peptide ligand Gly-Pro-Arg-Pro-amide ([[3hus]])
 {{TOC limit|limit=2}}
-==Fibrinogen==
+==3D Structure of Fibrinogen==
-Fibrinogen is composed of 3 non-identical chains alpha, beta, gamma (Fba, Fbb, Fbg) .  Fibrinogen is cleaved by thrombin which exposes Knobs A & B to form fibrin - the blood clotting protein.
-==3D Structure of Fibrinogen==
+Fibrinogen is composed of 3 non-identical chains alpha, beta, gamma (Fba, Fbb, Fbg) .
 ===Fibrinogen alpha+beta+gamma chains===