Villin: Difference between revisions
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[[Image:2k6n.png|left|300px]] | [[Image:2k6n.png|left|300px]] | ||
{{STRUCTURE_2k6n| PDB=2k6n | SCENE= |CAPTION=Human Supervillin Headpiece, [[2k6n]] }} | {{STRUCTURE_2k6n| PDB=2k6n | SCENE=Villin/Cv/1 |CAPTION=Human Supervillin Headpiece, [[2k6n]] }} | ||
'''3D Structure of Villin''' <br /> | '''3D Structure of Villin''' <br /> | ||
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== Advillin == | === Advillin === | ||
[[1und]] – hAVIL headpiece<br /> | [[1und]] – hAVIL headpiece<br /> | ||
Revision as of 15:03, 22 July 2010
3D Structure of Villin
The image at the top is a human Human Supervillin Headpiece (3ffn)
VillinVillin
Villin (VIL) is an actin-binding protein. It contains gelsolin-like domains in its N-terminal and a helical headpiece which binds actin. Supervillin (SVIL) contains gelsolin-like domains in its C-terminal and interacts with actin. Advillin (AVIL) is another actin-binding protein in the gelsolin family which is expressed in the peripheral sensory neurons.
3D Structures of Villin3D Structures of Villin
SupervillinSupervillin
2k6m, 2k6n – hSVIL headpiece– human – NMR
VillinVillin
3fg7 – hVIL gelsolin domains 4-6
1unc – hVIL headpiece
2rjw, 2rjx, 2rjv, 2rjy, 1yu7, 1yu8 – cVIL headpiece (mutant) – chicken
1yu5, 1qqv - cVIL headpiece
1vii, 2vik, 2vil - cVIL headpiece - NMR
2ppz, 2jm0 - VIL headpiece (mutant) – synthetic – NMR
2f4k, 1wy3, 1wy4, 1yrf, 1yri - VIL fragment (mutant) – synthetic
AdvillinAdvillin
1und – hAVIL headpiece