1juj: Difference between revisions
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[[Image:1juj.png|left|200px]] | [[Image:1juj.png|left|200px]] | ||
{{STRUCTURE_1juj| PDB=1juj | SCENE= }} | {{STRUCTURE_1juj| PDB=1juj | SCENE= }} | ||
===Human Thymidylate Synthase Bound to dUMP and LY231514, a Pyrrolo(2,3-d)pyrimidine-based Antifolate=== | ===Human Thymidylate Synthase Bound to dUMP and LY231514, a Pyrrolo(2,3-d)pyrimidine-based Antifolate=== | ||
{{ABSTRACT_PUBMED_11697906}} | {{ABSTRACT_PUBMED_11697906}} | ||
==About this Structure== | ==About this Structure== | ||
[[1juj]] is a 4 chain structure of [[Thymidylate synthase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JUJ OCA]. | |||
==See Also== | |||
*[[Thymidylate synthase|Thymidylate synthase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:011697906</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Thymidylate synthase]] | [[Category: Thymidylate synthase]] | ||
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[[Category: Drug resistance]] | [[Category: Drug resistance]] | ||
[[Category: Dtmp synthesis]] | [[Category: Dtmp synthesis]] | ||
[[Category: Transferase]] | |||
Revision as of 09:00, 26 July 2012
Human Thymidylate Synthase Bound to dUMP and LY231514, a Pyrrolo(2,3-d)pyrimidine-based AntifolateHuman Thymidylate Synthase Bound to dUMP and LY231514, a Pyrrolo(2,3-d)pyrimidine-based Antifolate
Template:ABSTRACT PUBMED 11697906
About this StructureAbout this Structure
1juj is a 4 chain structure of Thymidylate synthase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Sayre PH, Finer-Moore JS, Fritz TA, Biermann D, Gates SB, MacKellar WC, Patel VF, Stroud RM. Multi-targeted antifolates aimed at avoiding drug resistance form covalent closed inhibitory complexes with human and Escherichia coli thymidylate synthases. J Mol Biol. 2001 Nov 2;313(4):813-29. PMID:11697906 doi:10.1006/jmbi.2001.5074