Template:STRUCTURE 1s8o: Difference between revisions

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{{Structure
{{Structure
|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[1s8o]], resolution 2.60&Aring; (<scene name='initialview01'>default scene</scene>)}}}
|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[1s8o]], [[Resolution|resolution]] 2.60&Aring; (<scene name='initialview01'>default scene</scene>)}}}
|LIGAND= <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene>
|LIGAND= <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Microsomal_epoxide_hydrolase Microsomal epoxide hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.3.2.9 3.3.2.9] </span>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Hydrolase Hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.3.2.9 and 3.3.2.10 3.3.2.9 and 3.3.2.10] </span>
|GENE= EPHX2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|GENE= EPHX2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam00561 Abhydrolase_1], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG2267 PldB], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1011 COG1011]</span>
|RELATEDENTRY=[[1vj5|1vj5]]
|RELATEDENTRY=[[1vj5|1vj5]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1s8o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s8o OCA], [http://www.ebi.ac.uk/pdbsum/1s8o PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1s8o RCSB]</span>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1s8o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s8o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1s8o RCSB], [http://www.ebi.ac.uk/pdbsum/1s8o PDBsum]</span>
|FUNCTION={{GO|id=GO:0000287 | text = magnesium ion binding}}{{GO|id=GO:0003824 | text = catalytic activity}}{{GO|id=GO:0004301 | text = epoxide hydrolase activity}}{{GO|id=GO:0046872 | text = metal ion binding}}{{GO|id=GO:0016787 | text = hydrolase activity}}{{GO|id=GO:0042803 | text = protein homodimerization activity}}
|FUNCTION={{GO|id=GO:0000287 | text = magnesium ion binding}}{{GO|id=GO:0003824 | text = catalytic activity}}{{GO|id=GO:0004301 | text = epoxide hydrolase activity}}{{GO|id=GO:0046872 | text = metal ion binding}}{{GO|id=GO:0016787 | text = hydrolase activity}}{{GO|id=GO:0042803 | text = protein homodimerization activity}}
|PROCESS={{GO|id=GO:0006800 | text = oxygen and reactive oxygen species metabolic process}}{{GO|id=GO:0006874 | text = cellular calcium ion homeostasis}}{{GO|id=GO:0006954 | text = inflammatory response}}{{GO|id=GO:0009636 | text = response to toxin}}{{GO|id=GO:0008152 | text = metabolic process}}{{GO|id=GO:0045909 | text = positive regulation of vasodilation}}{{GO|id=GO:0006805 | text = xenobiotic metabolic process}}{{GO|id=GO:0017144 | text = drug metabolic process}}{{GO|id=GO:0006725 | text = aromatic compound metabolic process}}{{GO|id=GO:0019439 | text = aromatic compound catabolic process}}{{GO|id=GO:0008217 | text = regulation of blood pressure}}
|PROCESS={{GO|id=GO:0006800 | text = oxygen and reactive oxygen species metabolic process}}{{GO|id=GO:0006874 | text = cellular calcium ion homeostasis}}{{GO|id=GO:0006954 | text = inflammatory response}}{{GO|id=GO:0009636 | text = response to toxin}}{{GO|id=GO:0008152 | text = metabolic process}}{{GO|id=GO:0045909 | text = positive regulation of vasodilation}}{{GO|id=GO:0006805 | text = xenobiotic metabolic process}}{{GO|id=GO:0017144 | text = drug metabolic process}}{{GO|id=GO:0006725 | text = aromatic compound metabolic process}}{{GO|id=GO:0019439 | text = aromatic compound catabolic process}}{{GO|id=GO:0008217 | text = regulation of blood pressure}}
|COMPONENT={{GO|id=GO:0005777 | text = peroxisome}}{{GO|id=GO:0005625 | text = soluble fraction}}{{GO|id=GO:0005829 | text = cytosol}}{{GO|id=GO:0005737 | text = cytoplasm}}
|COMPONENT={{GO|id=GO:0005777 | text = peroxisome}}{{GO|id=GO:0005625 | text = soluble fraction}}{{GO|id=GO:0005829 | text = cytosol}}{{GO|id=GO:0005737 | text = cytoplasm}}
|SARESOURCES=<span class='plainlinks'>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR011945 Ipr011945], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR005834 Ipr005834], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR006402 Ipr006402], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR003089 Ipr003089], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR005833 Ipr005833], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000639 Ipr000639], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000073 Ipr000073]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00702 PF00702], [http://pfam.sanger.ac.uk/family?acc=PF00561 PF00561]<br>SCOP : [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=98737 d1s8oa2], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=98736 d1s8oa1]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P34913 P34913]</span>
|SARESOURCES=<span class='plainlinks'>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR011945 Ipr011945], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR005834 Ipr005834], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR006402 Ipr006402], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR003089 Ipr003089], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR005833 Ipr005833], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000639 Ipr000639], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000073 Ipr000073]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00702 PF00702], [http://pfam.sanger.ac.uk/family?acc=PF00561 PF00561]<br>SCOP : [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=98737 d1s8oa2], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=98736 d1s8oa1]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P34913 P34913]</span>
|FARESOURCES=<span class='plainlinks'>GeneCard : [http://www.genecards.org/cgi-bin/carddisp.pl?id=EPHX2 EPHX2]</span>
|uPDB=1S8O|CONSURF={{!}}-
|CONSURF={{!}}-
{{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]]
{{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]]
{{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;"
{{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;"

Latest revision as of 12:57, 4 January 2013

Drag the structure with the mouse to rotate
1s8o, resolution 2.60Å ()
Ligands:
Gene: EPHX2 (Homo sapiens)
Activity: Hydrolase, with EC number and 3.3.2.10 3.3.2.9 and 3.3.2.10
Related: 1vj5
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml


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