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Template
:
STRUCTURE 1s8o
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Asymmetric Unit
Biological Assembly
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1s8o
,
resolution
2.60Å (
)
Ligands
:
Gene
:
EPHX2 (
Homo sapiens
)
Activity
:
Hydrolase
, with EC number
and 3.3.2.10 3.3.2.9 and 3.3.2.10
Related
:
1vj5
Structural annotation
:
Resources:
InterPro :
Ipr011945
,
Ipr005834
,
Ipr006402
,
Ipr003089
,
Ipr005833
,
Ipr000639
,
Ipr000073
Pfam :
PF00702
,
PF00561
SCOP :
d1s8oa2
,
d1s8oa1
UniProt :
P34913
Functional annotation
:
Cellular component
:
peroxisome
soluble fraction
cytosol
cytoplasm
Biological process
:
oxygen and reactive oxygen species metabolic process
cellular calcium ion homeostasis
inflammatory response
response to toxin
metabolic process
positive regulation of vasodilation
xenobiotic metabolic process
drug metabolic process
aromatic compound metabolic process
aromatic compound catabolic process
regulation of blood pressure
Molecular function
:
magnesium ion binding
catalytic activity
epoxide hydrolase activity
metal ion binding
hydrolase activity
protein homodimerization activity
Evolutionary conservation
:
Toggle Conservation Colors:
Rows = identical sequences:
Further Information:
Caveats
,
Explanation
,
Complete Results at ConSurfDB
Resources:
FirstGlance
,
OCA
,
RCSB
,
PDBsum
Coordinates
:
save as
pdb
,
mmCIF
,
xml
proteopedia link