8uk9: Difference between revisions

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'''Unreleased structure'''


The entry 8uk9 is ON HOLD  until Paper Publication
==Structure of T4 Bacteriophage clamp loader mutant D110C bound to the T4 clamp, primer-template DNA, and ATP analog==
 
<StructureSection load='8uk9' size='340' side='right'caption='[[8uk9]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8uk9]] is a 20 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8UK9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8UK9 FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=AF3:ALUMINUM+FLUORIDE'>AF3</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8uk9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8uk9 OCA], [https://pdbe.org/8uk9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8uk9 RCSB], [https://www.ebi.ac.uk/pdbsum/8uk9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8uk9 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LOADS_BPT4 LOADS_BPT4] Forms the sliding-clamp-loader together with the small subunit (PubMed:10585481). The clamp loader holds the clamp in an open conformation and places it onto the DNA (PubMed:22194570).[HAMAP-Rule:MF_04163]<ref>PMID:10585481</ref> <ref>PMID:22194570</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia virus T4]]
[[Category: Large Structures]]
[[Category: Gee CL]]
[[Category: Ghaffari-Kashani S]]
[[Category: Marcus K]]

Latest revision as of 14:48, 13 December 2023

Structure of T4 Bacteriophage clamp loader mutant D110C bound to the T4 clamp, primer-template DNA, and ATP analogStructure of T4 Bacteriophage clamp loader mutant D110C bound to the T4 clamp, primer-template DNA, and ATP analog

Structural highlights

8uk9 is a 20 chain structure with sequence from Escherichia virus T4. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 3.1Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

LOADS_BPT4 Forms the sliding-clamp-loader together with the small subunit (PubMed:10585481). The clamp loader holds the clamp in an open conformation and places it onto the DNA (PubMed:22194570).[HAMAP-Rule:MF_04163][1] [2]

References

  1. ↑ Janzen DM, Torgov MY, Reddy MK. In vitro reconstitution of the bacteriophage T4 clamp loader complex (gp44/62). J Biol Chem. 1999 Dec 10;274(50):35938-43. PMID:10585481 doi:10.1074/jbc.274.50.35938
  2. ↑ Kelch BA, Makino DL, O'Donnell M, Kuriyan J. How a DNA polymerase clamp loader opens a sliding clamp. Science. 2011 Dec 23;334(6063):1675-80. PMID:22194570 doi:10.1126/science.1211884

8uk9, resolution 3.10Å

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