8uk9

Structure of T4 Bacteriophage clamp loader mutant D110C bound to the T4 clamp, primer-template DNA, and ATP analogStructure of T4 Bacteriophage clamp loader mutant D110C bound to the T4 clamp, primer-template DNA, and ATP analog

Structural highlights

8uk9 is a 20 chain structure with sequence from Escherichia virus T4. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 3.1Å
Ligands:	, ,
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

LOADS_BPT4 Forms the sliding-clamp-loader together with the small subunit (PubMed:10585481). The clamp loader holds the clamp in an open conformation and places it onto the DNA (PubMed:22194570).[HAMAP-Rule:MF_04163]^[1] ^[2]

References

↑ Janzen DM, Torgov MY, Reddy MK. In vitro reconstitution of the bacteriophage T4 clamp loader complex (gp44/62). J Biol Chem. 1999 Dec 10;274(50):35938-43. PMID:10585481 doi:10.1074/jbc.274.50.35938
↑ Kelch BA, Makino DL, O'Donnell M, Kuriyan J. How a DNA polymerase clamp loader opens a sliding clamp. Science. 2011 Dec 23;334(6063):1675-80. PMID:22194570 doi:10.1126/science.1211884

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

[1] Janzen DM, Torgov MY, Reddy MK. In vitro reconstitution of the bacteriophage T4 clamp loader complex (gp44/62). J Biol Chem. 1999 Dec 10;274(50):35938-43. PMID:10585481 doi:10.1074/jbc.274.50.35938

[2] Kelch BA, Makino DL, O'Donnell M, Kuriyan J. How a DNA polymerase clamp loader opens a sliding clamp. Science. 2011 Dec 23;334(6063):1675-80. PMID:22194570 doi:10.1126/science.1211884

[1]

[2]

8uk9

Structure of T4 Bacteriophage clamp loader mutant D110C bound to the T4 clamp, primer-template DNA, and ATP analogStructure of T4 Bacteriophage clamp loader mutant D110C bound to the T4 clamp, primer-template DNA, and ATP analog

Structural highlights

Function

References

Contents

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Navigation menu

8uk9

Structure of T4 Bacteriophage clamp loader mutant D110C bound to the T4 clamp, primer-template DNA, and ATP analogStructure of T4 Bacteriophage clamp loader mutant D110C bound to the T4 clamp, primer-template DNA, and ATP analog

Structural highlights

Function

References

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Navigation menu

Search