Nonstructural protein 3D structures

3D Structures of Nonstructural protein3D Structures of Nonstructural protein

Updated on 18-February-2021

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• Nonstructural protein
  • 3o9q, 4opa, 4oph – IvNS1 (mutant) – Influenza virus
    
  • 3o9r, 3o9s, 3o9t, 3o9u, 3f5t – IvNS1
    
  • 3m8a, 2z0a, 1xeq, 1ail – IvNS1 RNA-binding domain
    
  • 3p31 – IvNS1 C terminal effector domain
    
  • 3p38, 3p39 – IvNS1 C terminal effector domain (mutant)
    
  • 1ns1 - IvNS1 RNA-binding domain - NMR
    
  • 3m5r, 2gx9 - IvNS1 effector domain
    
  • 1pd3 – IvNS2 M1-binding domain
    
  • 3l6p, 3lkw – DvNS2B/3 protease domain (mutant) – Dengue virus
    
  • 4r05 – DvNS5 residues 2491-2752
    
  • 2o1j – RvNSP4 diarrhea-inducing domain – human rotavirus
    
  • 2gu0 – RvNS2
    
  • 5y2h, 5y2j, 5y9r – NSP4 diarrhea-inducing domain – bovine rotavirus
    
  • 2ajj, 2ajm, 2ajn, 2ajo – NS5A membrane-anchor domain – bovine viral diarrhea virus – NMR
    
  • 1fw5 – NSP1 membrane-binding domain – Semliki forest virus – NMR
    
  • 5vj2 – NS1 – respiratory syncytial virus
    
  • 5i65 – NS ORF1A – porcine reproductive and respiratory syndrome virus
    
  • 1qol – NSP20A (mutant) - Foot-and-mouth disease virus
    
  • 1nhu – HvNS5B RNA-dependent RNA polymerase residues 2420-2989 – Hepatitis C virus
    
  • 1r7c, 1r7d, 1r7e, 1r7f, 1r7g - HvNS5A membrane-anchor domain - NMR
    
  • 2gdt, 2hsx – SvNS1 (mutant) – Sars coronavirus – NMR
    
  • 7jtl – Sv2NS8 residues 18-121 – Sars-cov-2
    
  • 7k3n, 7k7p – Sv2NS1
    
  • 6w9c – Sv2NS3 residues 1564-1878
    
  • 6zct, 6zpe – Sv2NS10 residues 4263-4384
    
  • 2jzd, 2jze, 2jzf, 2rnk – SvNS3 residues 527-651 – NMR
    
  • 2kaf - SvNS3 residues 1473-1532 – NMR
    
  • 2kys – SvNS7 – NMR
    
  • 2l8k – NS7 residues 1454-1575 – NMR
    
  • 3mtv – NS1 residues 181-383 – PRRS virus
    
  • 3zfn, 3zfo, 3zfq, 3zfp, 3zfr, 3zft, 3zfu – Npro (mutant) – Pestivirus
    
  • 4x2z – NS3 residues 1174-1483 – Avian infectious bronchitis virus
    
• Nonstructural protein complex
  • 2xbm – DvNS5 methyltransferase domain + RNA
    
  • 3p8z - DvNS5 methyltransferase domain + SAH + inhibitor
    
  • 5cuq - DvNS5 methyltransferase domain + inhibitor
    
  • 5fc8 - DvNS5 C-terminal + importin
    
  • 2hye – SvNSV + DNA damage-binding protein + cullin-4A + ring-box protein – Simian virus 5
    
  • 2b5l - SvNSV + DNA damage-binding protein
    
  • 1nhv, 1nhu – HvNS5B RNA-dependent RNA polymerase residues 2420-2989 + inhibitor
    
  • 1dxp, 1dy8, 1dy9, 1w3c – HvNS4A + HvHelicase NS3
    
  • 4k8b - HvNS4A + HvProtease NS3 + inhibitor
    
  • 4a1t, 4a1x - HvNS4A + peptide inhibitor
    
  • 3phe – HvNS5B + quinolone derivative
    
  • 3ub0 – NSP6 + NSP7 – Feline infectious peritonitis virus
    
  • 1knz – RvNSP34 N terminal + mRNA
    
  • 1lj2 – RvNSP34 C terminal + eukaryotic protein synthesis initiation factor peptide
    
  • 4r8r – DvNS5 residues 2491-2752 + adenosyl-Met
    
  • 4r8s – DvNS5 residues 2491-2752 + sinefungin
    
  • 6ux2 – NS5 residues 2789-3419 + P113 – Zika virus
    
  • 6zlw, 6zoj, 6zok, 6zol, 7k5i – Sv2NS1 in human 40S ribosome – Cryo EM
    
  • 6zmt, 6zn5 – Sv2NS1 in human pre-40S-like ribosome – Cryo EM
    
  • 6zp4, 6zon – Sv2NS1 in human 43S ribosome – Cryo EM
    
  • 6zm7, 6zme, 6zmi, 6zmo – Sv2NS1 in human 80S ribosome – Cryo EM
    
  • 7jqb, 7jqc – Sv2NS1 in rabbit 40S ribosome – Cryo EM
    
  • 5f22, 6m5i, 6wiq, 6wqd, 6wtc, 6xip, 6yhu, 7jlt – Sv2NS7 residues 3860-3930 + Sv2NS8 residues 4018-4134
    
  • 6xqb – Sv2NS7 residues 3860-3930 + Sv2NS8 residues 4018-4134 + RNA – Cryo EM
    
  • 7c2k – Sv2NS7 residues 3860-3930 + Sv2NS8 residues 4018-4134 + Sv2NS12 residues 4393-5324 + RNA
    
  • 6m71, 7btf, 7bv1, 7bw4 – Sv2NS7 residues 3860-3930 + Sv2NS8 residues 4018-4134 + Sv2NS12 residues 4393-5324 – Cryo EM
    
  • 6yyt, 7bzf – Sv2NS7 residues 3860-3930 + Sv2NS8 residues 4018-4134 + Sv2NS12 residues 4393-5324 + RNA – Cryo EM
    
  • 7aap, 7b3b, 7b3c, 7bv2, 7ctt – Sv2NS7 residues 3860-3930 + Sv2NS8 residues 4018-4134 + Sv2NS12 residues 4393-5324 + RNA + drug – Cryo EM
    
  • 7b3d – Sv2NS7 residues 3860-3930 + Sv2NS8 residues 4018-4134 + Sv2NS12 residues 4393-5324 + RNA + AMP – Cryo EM
    
  • 6xez, 7cxm, 7cxn, 7cyq – Sv2NS7 residues 3860-3930 + Sv2NS8 residues 4018-4134 + Sv2NS12 residues 4393-5324 + Sv2NS13 residues 5325-5925 + RNA – Cryo EM
    
  • 6w4h – Sv2NS16 residues 6799-7096 + Sv2NS10 residues 4254-4392
    
  • 6w61, 6w75, 6wvn, 6xkm, 7bq7, 7c2i, 7c2j, 7jpe, 7koa – Sv2NS16 residues 6799-7096 + Sv2NS10 residues 4254-4392 + SAM
    
  • 6wjt, 6wq3, 6wrz, 7jhe – Sv2NS16 residues 6799-7096 + Sv2NS10 residues 4254-4392 + SAH
    
  • 7jib – Sv2NS16 residues 6799-7096 + Sv2NS10 residues 4254-4392 + SAH + SAM
    
  • 7jyy – Sv2NS16 residues 6799-7096 + Sv2NS10 residues 4254-4392 + SAM + RNA
    
  • 6kws – Sv2NS16 residues 6799-7096 + Sv2NS10 residues 4254-4392 + SAM + GpppA
    
  • 7jz0, 7l6r, 7l6t – Sv2NS16 residues 6799-7096 + Sv2NS10 residues 4254-4392 + SAH + RNA
    
  • 6wkq, 6yz1 – Sv2NS16 residues 6799-7096 + Sv2NS10 residues 4254-4392 + sinefungin
    
  • 6yyt – Sv2NS12 residues 4393-5324 + Sv2NS8 residues 3943-4140 + Sv2NS7 residues 3860-3942 + RNA