7cvv: Difference between revisions

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'''Unreleased structure'''


The entry 7cvv is ON HOLD  until Paper Publication
==Crystal structure of Catechol o-methyl transferase (COMT) from Niastella koreensis==
<StructureSection load='7cvv' size='340' side='right'caption='[[7cvv]], [[Resolution|resolution]] 2.52&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7cvv]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Niastella_koreensis_GR20-10 Niastella koreensis GR20-10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CVV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CVV FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.52&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7cvv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cvv OCA], [https://pdbe.org/7cvv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7cvv RCSB], [https://www.ebi.ac.uk/pdbsum/7cvv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7cvv ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CAMT_NIAKG CAMT_NIAKG] Catechol O-methyltransferase that can use various catechol-like compounds (PubMed:33596655). Can produce vanillic acid (meta-form) and iso-vanillic acid (para-form) from protocatechuic acid (PCA) (PubMed:33596655). Does not have a regiospecificity, and produces the meta- and para-forms of the products in equal proportion (PubMed:33596655).<ref>PMID:33596655</ref>


Authors: Kim, B., Lee, S.H., Kim, K.-J.
==See Also==
 
*[[Catechol O-methyltransferase 3D structures|Catechol O-methyltransferase 3D structures]]
Description: Crystal structure of Catechol o-methyl transferase (COMT) from Niastella koreensis
== References ==
[[Category: Unreleased Structures]]
<references/>
[[Category: Kim, K.-J]]
__TOC__
[[Category: Lee, S.H]]
</StructureSection>
[[Category: Kim, B]]
[[Category: Large Structures]]
[[Category: Niastella koreensis GR20-10]]
[[Category: Kim B]]
[[Category: Kim K-J]]
[[Category: Lee SH]]

Latest revision as of 19:17, 29 November 2023

Crystal structure of Catechol o-methyl transferase (COMT) from Niastella koreensisCrystal structure of Catechol o-methyl transferase (COMT) from Niastella koreensis

Structural highlights

7cvv is a 3 chain structure with sequence from Niastella koreensis GR20-10. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.52Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CAMT_NIAKG Catechol O-methyltransferase that can use various catechol-like compounds (PubMed:33596655). Can produce vanillic acid (meta-form) and iso-vanillic acid (para-form) from protocatechuic acid (PCA) (PubMed:33596655). Does not have a regiospecificity, and produces the meta- and para-forms of the products in equal proportion (PubMed:33596655).[1]

See Also

References

  1. ↑ Lee SH, Kim B, Kim KJ. Crystal Structure and Regiospecificity of Catechol O-Methyltransferase from Niastella koreensis. J Agric Food Chem. 2021 Mar 3;69(8):2531-2538. PMID:33596655 doi:10.1021/acs.jafc.0c07621

7cvv, resolution 2.52Å

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