2nu4: Difference between revisions

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==Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I==
==Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I==
<StructureSection load='2nu4' size='340' side='right' caption='[[2nu4]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
<StructureSection load='2nu4' size='340' side='right'caption='[[2nu4]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2nu4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Melga Melga] and [http://en.wikipedia.org/wiki/Streptomyces_griseus Streptomyces griseus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NU4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2NU4 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2nu4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Melga Melga] and [http://en.wikipedia.org/wiki/Streptomyces_griseus Streptomyces griseus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NU4 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2NU4 FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3sgb|3sgb]], [[2nu0|2nu0]], [[2nu1|2nu1]], [[2nu2|2nu2]], [[2nu3|2nu3]], [[4sga|4sga]], [[1mct|1mct]], [[1hja|1hja]]</td></tr>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3sgb|3sgb]], [[2nu0|2nu0]], [[2nu1|2nu1]], [[2nu2|2nu2]], [[2nu3|2nu3]], [[4sga|4sga]], [[1mct|1mct]], [[1hja|1hja]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Streptogrisin_B Streptogrisin B], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.81 3.4.21.81] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Streptogrisin_B Streptogrisin B], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.81 3.4.21.81] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2nu4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nu4 OCA], [http://pdbe.org/2nu4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2nu4 RCSB], [http://www.ebi.ac.uk/pdbsum/2nu4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2nu4 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2nu4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nu4 OCA], [http://pdbe.org/2nu4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2nu4 RCSB], [http://www.ebi.ac.uk/pdbsum/2nu4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2nu4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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==See Also==
==See Also==
*[[Proteinase|Proteinase]]
*[[Proteinase|Proteinase]]
*[[Proteinase 3D structures|Proteinase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Melga]]
[[Category: Melga]]
[[Category: Streptogrisin B]]
[[Category: Streptogrisin B]]

Revision as of 09:35, 20 May 2020

Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18IAccommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I

Structural highlights

2nu4 is a 2 chain structure with sequence from Melga and Streptomyces griseus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Activity:Streptogrisin B, with EC number 3.4.21.81
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[PRTB_STRGR] Has a primary specificity for large aliphatic or aromatic amino acids.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2nu4, resolution 1.75Å

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