1zr9: Difference between revisions

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==Solution Structure of a Human C2H2-type Zinc Finger Protein==
==Solution Structure of a Human C2H2-type Zinc Finger Protein==
<StructureSection load='1zr9' size='340' side='right' caption='[[1zr9]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='1zr9' size='340' side='right'caption='[[1zr9]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1zr9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZR9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZR9 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1zr9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZR9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZR9 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ZNF593 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ZNF593 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zr9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zr9 OCA], [http://pdbe.org/1zr9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zr9 RCSB], [http://www.ebi.ac.uk/pdbsum/1zr9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1zr9 ProSAT], [http://www.topsan.org/Proteins/CESG/1zr9 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zr9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zr9 OCA], [https://pdbe.org/1zr9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zr9 RCSB], [https://www.ebi.ac.uk/pdbsum/1zr9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zr9 ProSAT], [https://www.topsan.org/Proteins/CESG/1zr9 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ZN593_HUMAN ZN593_HUMAN]] Negatively modulates the DNA binding activity of Oct-2 and therefore its transcriptional regulatory activity. Could act either by binding to DNA octamer or by interacting with Oct-2. May also be a modulator of other octamer-binding proteins.  
[[https://www.uniprot.org/uniprot/ZN593_HUMAN ZN593_HUMAN]] Negatively modulates the DNA binding activity of Oct-2 and therefore its transcriptional regulatory activity. Could act either by binding to DNA octamer or by interacting with Oct-2. May also be a modulator of other octamer-binding proteins.  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]
[[Category: Lytle, B L]]
[[Category: Lytle, B L]]

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