1tmw: Difference between revisions

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==Solution structure of Human Coactosin Like Protein D123N==
==Solution structure of Human Coactosin Like Protein D123N==
<StructureSection load='1tmw' size='340' side='right' caption='[[1tmw]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='1tmw' size='340' side='right'caption='[[1tmw]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1tmw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TMW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1TMW FirstGlance]. <br>
<table><tr><td colspan='2'>[[1tmw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TMW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1TMW FirstGlance]. <br>
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Dai, H]]
[[Category: Dai, H]]
[[Category: Ding, H]]
[[Category: Ding, H]]

Revision as of 16:30, 25 December 2019

Solution structure of Human Coactosin Like Protein D123NSolution structure of Human Coactosin Like Protein D123N

Structural highlights

1tmw is a 1 chain structure with sequence from Human. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[COTL1_HUMAN] Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. Provost P, Doucet J, Stock A, Gerisch G, Samuelsson B, Radmark O. Coactosin-like protein, a human F-actin-binding protein: critical role of lysine-75. Biochem J. 2001 Oct 15;359(Pt 2):255-63. PMID:11583571
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