1tmw

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Solution structure of Human Coactosin Like Protein D123NSolution structure of Human Coactosin Like Protein D123N

Structural highlights

1tmw is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

COTL1_HUMAN Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. Provost P, Doucet J, Stock A, Gerisch G, Samuelsson B, Radmark O. Coactosin-like protein, a human F-actin-binding protein: critical role of lysine-75. Biochem J. 2001 Oct 15;359(Pt 2):255-63. PMID:11583571
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OCA